Syphilis Word Scramble

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Question	Answer
Syphillis is caused by a cork screw bacteria called......	Treponema pallidum
True or false: syphillis stains silver	true
can syphillis be grown in vitro?	no
Can Syphillis mutate	no, its genome its conserved and stable. Susceptible to penicillin
True or False: T pallidum is destroyed easily	true; a variety of physical and chemical agents like soap and water
Describe the pathology	t palliudum enters through abrasions or through unbroken skin by hair follicles
If the circulatory system is attacked by the bactera what happens?	it affects the lymphatic system and bloodstream
Describe primary syphillis stage	spirochetal load increases and forms a chancre at inoculation site
true or false: Chancre lesions may not develop in every case. They are highly infectious.	Both statements are true
Describe each primary stage	Red, painless papule Base of the chancre is smooth but the borders are raised and indurated Ulceration occurs with exudate present when secondarily infected Crusts over and heals spontaneously, disappearing within a few weeks
What are the dental implications	lips, tongue, oral mucosa
Describe secondary syphilis	after the chancre has formed (2-8 weeks) may or may not still be present. Spirochetal load at its peak. Flu like symptoms. Skin rash on face, feet, hands. Mucous patch appears.
Describe a mucous patch and where it occurs	A painless shallow ulcer that forms on the lips, soft palate, tongue. Its grayish white red looking.
Alopecia occurs in Secondary syphilis
Describe latent syphilis	Begins when the symptom of secondary disappears. It is only detectable by blood work.
Describe Early Latent syphilis	clinical symptoms appear during the 1st year
Describe Late Latent Syphilis	Bacteria is destroying the internal organs inside but there is no symptoms on the outside
Describe tertiary latent syphiliis	destructive stage of the disease. Sub divided into neuro, cardiovascular, gummatous.
Describe gumma	a granuloma lesion on the skin and bones. Responds dramatically to antimicrobial therapy. Develops after 5-30 yrs after infection of 15% of untreated infections.
Describe neurosyphilis	invasion of the CNS in early syphilis. symptoms dont show until 5-10 yrs
What percentage of tertiary syphillis neurosyphilis occur	8% of untreated cases
What are major clinical signs of tertiary syphilis	-paresis: paralysis -Tabes Dorsalis: intense pains, incoordination, functional disturbances of most organs -Personality changes
Describe Cardiovascular	aoritis- the elastic tissue of the aorta is replaced by fibrous tissue
Describe complications of aoritis	aortic regurgitation obstruction of the coronary arteries aortic aneurysm aortic valve incompetence
Prenatal Syphilis	among those who survive infancy, 40% develop late symptoms of syphilis
describe prenatal syphilis	Cutaneous lesions much like secondary syphilis in the adult.
describe late prenatal syphilis	Hutchinson incisors and first molars with defective and/or supernumerary cusps
When diagnosed and treated in its early stages, syphilis is easy to cure.
What is the treatment for symphilis	penicillin g given parenterally. A single injection of penicillin can stop the disease from progressing if you've been infected for less than a year. If you've had syphilis for longer than a year, you may need additional doses.

Created by: DH_Student