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MICRO ANTIMICROBIAL

action, use, mechanism, of antomicrobials

QuestionAnswer
action mechanism of pennicillin Beta Lactam disruption of peptidoglycan
antibiotic substance produced by an organism that is toxic to bacteria
antimicrobial chemical compound toxic to microbes.
Chemotherapy
prophylaxis
Erythromycin uses Streptococcal infections, syphilis,respiratory infections, mycoplasmal infections, Lyme disease;
AZT Antiviral, a NARTI, Blocks DNA replication of Virus
Beta-lactamase Enzyme evolved by bacteria to protect against beta lactam antibiotics
In vitro in a test tube or lab apparatus
Eye
Actinomycetes Actinomycetales are Gram positive
Penicillin Antibiotic segment/class that attacks cell wall (beta lactam) of bacteria. First discovered by Fleming
Cephalosporin Antibiotic segment/class that attacks cell wall (beta lactam) of bacteria. From cephalosporin mold
Aminoglycosides antibiotic class/segment that blocks protien synthesis by blocking 30s site on ribosome; ototoxic
Chloramphenicol blocks peptide formation
Antibacterial drugs which target protien synthesis (2 ) Streptomycin, Gentamycin/wpnmf////
Classes of drugs which attack cell wall (3 ) Penicillin, cephalosporins, Vancomycin/wall////
Classes of drugs which block protien synthesis @ Ribosome Aminoglycosides, Tetracyclines, Ketalods, Chloramphenicol, "mycins", lincosamides/protien////
Antibacterial drugs which attack cell wall (3 ) Bacitracin, Isoniazod, Vancomycin/wall/bacteriacide///
Classes of drugs which block folic acid Sulfonamides, Sulfones, trimethaprim/folic acid////
Classes of drugs which block DNA/RNA replication Flouroquinalones, rifampin/nucleics/bacteriacide///
Classes of drugs which block cell membrane polymixins,/membrane////
Major drug for tuberculosis Isoniazid/wall/bacteriacide///
major drug for fungal infection (widespread) Amphitericin B/membrane/fungicide///
magor drug for GI tract infections /////
Antivirals, modes of action (3) (1) penetration prevention, (2)translation/transcriptoin block, (3)maturation block/////
antimalarial drug chloroquin, /////
respiratory tract infections- Resistant Strep Pneumonia Ketek/////
Candidas yeast/fungal infections nystatin/////
Acne Clindomycin/protien/bacteriacide///
BBB crossers Cephalosporins, Gen 4/wall/bacteriacide/broad/High toxicity/
mitochondrial toxicity NARTI DRUGS, AZT, Retroviron/////
NARTI Nucleotide Analog reverse trnscriptiion inhibitors/////
Tetracycline Antibiotics, gram uses Gram -. Gram + rods and cocci, /protien/bacteriacide/broad/Low toxixity/
Tetracycline Antibiotics, uses diseases, (3) Rocky mountain S.F. Lymes, Mycoplasma Pnuemonia/protien/bacteriacide/broad//
Chloramphenicol Extremely toxic, /protien/bacteriacide/broad/High toxicity/
Erythromycin, used to treat: (4) Mycoplasma Pneum. ; legionellis, Chlamydia, pertussis/protien/bacteriacide/broad/Low toxixity/
Clindomycin broad spec/ GI sensitivity/protien/bacteriacide/broad/Low toxixity/
Streptomycin Aminoglycoside, used on B. Plague, tularemia, Tuberculosis/protien/bacteriacide/broad/High toxicity/neuro, ototoxic
Gentamycin Aminoglycoside, used on Gram neg. rods/protien/bacteriacide/broad/Low toxixity/
Rifampin Myobacterial infections, TB, Leprosy/nucleics/bacteriacide/narrow//
Grisofulvins Athletes foot , nephrotoxic/membrane/fungicide/narrow/High toxicity/nephro
polymixins DR Pseudomonas aeruginosa/membrane/bacteriacide/narrow/High toxicity/
Flucystocine mycoses/nucleics/fungicide/narrow/High toxicity/
Created by: jrjct1
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