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2010-07-15 #1.1
Comparison between Ulcerative colitis & Crohn's disease
Question | Answer |
---|---|
more common in whites than blacks; no sex predilection | both: ulcerative colitis and Crohn's disease |
smoking as risk factor | Crohn's disease |
limited to mucosa and submucosa | ulcerative colitis |
ileum and colon; involves mouth to anus; rectum spared: Dx? | Crohn's disease |
rectum; continuous into left colon; not involve other areas of GIT: Dx? | ulcerative colitis |
inflammatory pseudopolyps; friable, bloody residual mucosa; free hanging mesentery: Dx? | ulcerative colitis |
thick bowel wall; narrow lumen; skip lesions, strictures, fistulas; linear ulcer; cobblestone pattern mucosa; fat creeping around serosa: Dx? | Crohn's disease |
crypt abscesses containing neutrophil; ulcer; dysplasia: Dx? | ulcerative colitis |
noncaseating granuloma; lymphoid aggregates; X dysplasia: Dx? | Crohn's disease |
Rx: ulcerative colitis? | ASA preparations (sulfasalazine); infliximab; colectomy |
Rx: Crohn's disease? | corticosteroids; infliximab |
infliximab | both ulcerative colitis & Crohn's disease |
string sign in terminal ileum from luminal narrowing by inflammation; fistulas | Crohn's disease |
"lead pipe" appearance in chronic disease: Dx? Why "lead pipe"? | ulcerative colitis; loss of haustra > "lead pipe" appearance |
bloody diarrhea; recurrent left-sided abdominal cramping: Dx? | ulcerative colitis: rectum and left colon |
bloody diarrhea; recurrent right lower quadrant colikcy pain: Dx? | Crohn's disease: diarrhea could be watery or bloody |
extraintestinal manifestations in ulcerative colitis? | pyoderma gangrenosum; primary sclerosing cholangitis (UC > CD) |
extraintestinal manifestations in Crohn's disease? | migratory polyarthritis; erythema nodosum; ankylosing spondylitis; uveitis; immunologic disorders |
stricture; fistula; perianal disease; malabsorption(X bile salt); macrocytic anemia(X B12): Dx? | Crohn's disease: colon carcinoma (UC > CD) |
toxic megacolon; colorectal adenocarcinoma: Dx? | ulcerative colitis |
common extragastrointestinal manifestations; contrast? | primary sclerosing cholangitis (UC > CD); erythema nodosum; iritis (CD > UC); pyoderma gangrenosum; HLA27 association: UC with arthritis but CD with sarcollitis |