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Bio Defs Week 2

Textbook Definitions

TermDefinition
Lipid Fatty macromolecule that are soluble in organic solvents and insoluble in water, fats, oils, waxes, steroids & phospholipids
Hydrocarbons Organic molecule that contains only hydrogen & carbon atoms
Fatty Acids Lipid w/ a hydrocarbon chain bonded at one end to a carboxyl group, stores chemical energy
Saturated Lipids w/ only Carbon - Carbon single bonds, high melting points
Unsaturated Lipids w/ at least one Carbon - Carbon double bond, causes links in the hydrocarbon chain, low melting point
Waxes Long chains of non-polar lipid, fatty acids or long chain alcohols, solid
Oil Polysatured fat that is liquid at room temperature
Steroids Lipid w/ four-ring hydrocarbon structure, hormones, muscles, & immune system
Fats Lipids w/ three fatty acid molecules, insulation, long-term energy storage
Glycerol Three carbon molecules that form the “backbone” of phospholipids & fats
Ester Linkage Covalent bond, condensation reaction b/tw carboxyl & hydroxyl groups, joins fatty acids and glycerol to form a fat or phospholipid
Phospholipids Lipids w/ hydrophilic head & hydrophobic tail, major component for plasma membrane and organelle membrane
Amphipathic Substances w/ hydrophilic & hydrophobic regions, “dual-sympathy”
Amino Acids Small organic molecules that is the fundamental building block for protein, side chain
R-Group or Side Chain The part of an amino acid that makes different variations
Hydrophilic Active interaction w/ water, usually polar compounds w/ partial or fully charged atoms
Hydrophobic uninterested in interaction w/ water, usually nonpolar compounds
Peptide Bond Covalent bond formed by a condensation reaction b/tw two amino acids
Primary Structure Sequence of amino acids in a polypeptide chain, unfunctional, protein 1st stage
Secondary Structure Folding and coiling of primary structure, repeating configuration, alpha helix and beta pleated sheets, unfunctional, protein 2nd stage
Alpha Helix Second structure in a protein, polypeptide backbone spiral shape, h-bonds
Beta Pleated Sheet Second structure in protein, polypeptide backbone, folds into sheet-like shape, h-bond
Tertiary Structure 3-D interaction b/tw amion acid chain and R group, mutli-bonds, built from secondary structure, weaves and coils around, protein 3rd stage
Disulfide Bonds “Two sulfur” covalent bond, typically in the side chains, contribute to tertiary & quaternary levels
Quaternary Structure Result from aggregation of two or more polypeptide subunits, big from multi-little
Macromolecular Machines Group of proteins and nucleic acid that assemble to carry out a particular function
Polypeptide Amino acid chain > 50 residues, “many peptide”
Oligopeptide Amino acid chain < 50 residues, “few peptide”, aka peptide
Denatured Protein or nucleic acid, loss of 3-D structure due to breakage of covalent &/or non-covalent bonds, heat, chemical, PH, or salt
Molecular Chaperons Protein that facilitates folding or refolding into a 3-D shape
Prions Infectious particles made up of protein, two different fold shapes, normal fold & disease fold, infected can infect the uninfected
Catalysis Acceleration of a chemical reaction by adding a catalyst, usually an enzyme, activation energy
Catalyst Any substance that increases the rate of a chemical reaction w/o itself undergoing any permeate chemical change
Enzyme Protein catalyst used by living organisms to increase the rate of biological reactions
Substrates 1) a reactant that interacts w/ a catalyst, 2) Surface on which a cell or organism sits
Active Site Location on an enzyme molecule where substrates bind & react
Nucleic Acid Macromolecule composed of nucleotide monomers, store & transfer hereditary information, includes DNA & RNA
Nucleotides Building block of nucleic acid, nitrogen base, sugar (deoxyribose and ribose), and phosphate group, is comparable w/ nucleoside, but with more phosphate groups
Purines Class of double-ringed nitrogenous bases (A, G), found in nucleotides
Pyrimidines Class of single-ringed nitrogenous bases (C, U, T), found in nucleotides
Phosphodiester Linkage Chemical link b/tw adjacent nucleotide residues in DNA & RNA, forms when a phosphate group of a nucleotide condenses w/ the hydroxyl group on the sugar of a different nucleotide, phosphodiester bond
Ribonucleotides A nucleotide that contains ribose and a pentose sugar, is the basic building block for RNA
Deoxyribonucleotides A nucleotide that contains a deoxyribose and a pentose sugar, is the basic building block for DNA
X-Ray Crystallography Technique for determining 3-D structure of larger molecules, protein and nucleic acid, analysis diffraction patterns produced by x-ray beamed at crystals of the molecule
Antiparallel Two strands of a molecule, nucleic acid, are parallel but run in opposite directions
Complementary Base Pairing/ Watson-Crick Pairing Specific interactions between nitrogenous bases in DNA, A always pairs to T, and C always to G
Base Stacking Arrangement of nitrogen bases in DNA, bases stack on top of each other in a parallel configuration
Template Strand Original strand used as a base for a complementary strand, DNA synthesis
Complementary Strand New strand of DNA that connects to a temple strand, DNA synthesis
Ribozymes Any RNA Molecule that catalyses a chemical reaction
Condensation Reactions/Dehydration Synthesis Reaction w/ two or more molecules to form a larger molecule, reaction loses water
Hydrolysis Reaction to break down molecule by using water
Created by: KimbaPasch
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