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EXAM #1

Found Cell Biology

QuestionAnswer
Key Features of Cell -Enclosed by plasma membrane -controls entry and exit of substances -Organelles
Define Cell -All living organisms are made up of cells -Cell is the basic unit of structure and organization -Cells arise from pre-existing cells
Why are cells small? -as cell gets bigger, the SA:V ratio gets smaller (more volume, less membrane)
Fimbrae/pili -hairlike projections -used for adherence
Storage granules -area of the cell where nutrients are stored
flagellum -spin like a propeller -motility structures
Ribosomes (bacteria) -site of protein synthesis
Cell Wall (bacteria) -gives cell its shape -composed of peptidoglycan -tough, fibrous protective layer
Gram-Positive -Thick layer of peptidoglycan -Singular plasma membrane
Gram-Negative -thin peptidoglycan layer -double plasma membrane
Nucleoid -where dna is contain
Capsule -helps cells adhere -polysaccharide layer
Nucleus -contains most of DNA -site of DNA and RNA synthesis
Nuclear Envelope -inner membrane -outer membrane
Nuclear Pores -large complex of proteins that control entry and exit to the nucleus
Nuclear Import/Export -Import: importins bind protein with NLS to form "cargo complex" -importins return to cytosol
Nucleolus -site of ribosomal RNA synthesis and assembly of ribosomes -can have one or more
Ribosome (animals) -site of protein synthesis -particles composed of proteins and rRNA
Endomembrane System -Network of organelles involved in Vesicular transport
Vesicular transport
ER -surrounds nucleus -Extends into cytoplasm -connect to nuclear envelope
Rough ER -Protein assembly -incorporation into vesicle for transport from ER to next destination
Smooth ER -synthesis of lipids, carbohydrates, and steroid hormones
Golgi Apparatus -Protein sorting -can also modify of oligosaccharide chains addeded to proteins in ER
Cis Face -entry surface -receives vesicle from ER
Medial -middle region -in between cis and trans face
Trans face -exit surface -faces plasma membrane -site of transport
Lysosome -digest food -breaks down malfunctioning cell structures
Acid hydrolases -transported through ER to Golgi and budsto form lysosmes
Primary Lysosome -helps with cell metabolisms -ingests dissolving unwanted parts of the cell
Secondary Lysosome -breaking down enclosed materials -degrading extracellular material
Autophagy -gets rid of damage organelles within the cell
Vacuole -only found in plant/prokaryotic cell -digest nutrient -acts as a storage compartment -stores salt, some pigments and metabolic wastes
peroxisome -formed from budding from smooth ER -Oxidation of fatty acids -synthesize phospholipids -detoxify alcohol in liver cells -hydrogen peroxide is made as a by-product
Mitochondria -powerhouse -site of oxidative phosphorylation -enclosed by double membrane -Outer and Inner membrane
Chloroplasts -site of photosynthesis -light to chemical energy
Origins of Mitochondria -Theory of serial endosymbiosis
Origins of Chloroplasts -theory of serial endosymbiosis -where it was absorbed by a cell that already had a mitrocondra
Cytoskeleton -dense network of protein fibers -highly dynamic -give cells mechanical strength, shape, adn ability to move
Cilia -hairlike structures -beats in a whiplike fashion
Flagella -singular -longer and less numerous than cilia -9 fused pairs -2 unfused pairs -Anchored by basal body 9x3 organization -Movement produced by sliding up and down against each other
Cell Wall (animals) -provides structural support and protection -composed of polysaccharides and porteins
Monosaccharides -contains 3 to 7 sugars -all except dihydroxyacetone contain one or more chiral carbon atoms -simple sugars
Aldoses -monosaccharide whose carbon skeleton has an aldehyde group -primarily found in plants
Ketoses -monosaccharide whose carbon skeleton has a ketone group -only in presence of reducing sugar
Isomer D -most monosaccharides in living organisms are D stereoisomers
Isomer L -simple sugars
Cyclization A isomer -If hydroxyl groups is on opposite side it is Alpha
Cyclization B isomer -If hydroxyl group is on the same side it is BEta
Glycosidic Bonds -bonds formed between carbonyl carbon ofone suagr and any hydroxyl carbon on another sugar -Condensation -Hydrolysis
Disaccharides -Two monosaccharides linked by glycosidic bond
Lactose -made up of one alpha glucose and one beta galactose
Sucrose -made up of one alpha glucose and one beta fructose
Maltose -two alpha glucoses linked together
Bond Linkage of Disaccharides -linked by glycosidic bonds
Polysaccharides -macromolecules consisting of repeating units of simple suagr -plays important role in energy storage and structure -
Homopolysaccharides -Can be branched -Can be unbranched -all same monomers
Heteropolysaccharides -two different monomers that are either branched or unbranched
Starch -Repeating units of Alpha-D-Glucose -Can occur in two forms -Energy storage in plants
Glycogen -repeating units of Alpha-D-Glucose -Main storage of energy in animals
Function of Cellulose -structural component of plants -humans lack enzymes to break down cellulose
Structure of Cellulose -repeating units of Beta-D-glucose
Function of Chitin -provides structural support for cell walls of fungi -can form exoskeleton of arthropods
Structure of Chitin -composed of amino sugar derivative
Glycoproteins -half of mammalian proteins are glycoproteins -plays a role in protein-protein recognition -protein with small oligosaccharides attached
Glycolipids -lipids covalently bound to oligosaccharide -parts of plant and animal cell membranes -involved in cell-to-cell interactions
Lipids -most are amphipathic -energy source -membrane structure -cell signaling
Saturated FA -No double bonds between carbons and the chain
Unsaturated FA -One or more double bond between carbons in the the chain
Triacyclglycerols function -concentrated food reserve
Triacyclglycerols structure -Glycerol on top -three FA covalently linked to the Glycerol
Phospholipids function -can self-assemble into a double-layer to become bilayers
Phospholipids Asymmetric Bilayer assembly -can self-assemble in watery environment -Glycolipids -Phosphatidylinositols -on side facing outwards -the other side facing inwards
Membrane Fluidity function -Rapid Diffusion of Lipids and Proteins -Fusion of Vesicle -Even Distribution of Membrane lipids during Cell Divisiono
Membrane fluidity influences -length of FA tails -Saturation of FA -Cholesterol
Role of Cholesterol -fills spaces left by kinks of unsaturated FA tails -stiffens the bilayer
Two types of 5-Carbon Sugar -Deoxyribose -Ribose
Ribose -Found in RNA -has an oxygen containing ring
Deoxyribose -Found in DNA -has two chains that reads anti-parallel -held together by hydrogen bonds between the base portions -has a hydrogen containing ring
The linkage of carbon sugar -glycosidic bond
Phosphate groups -AMP -ATP -ADP
How many phosphates groups -5
Bonds involved in phosphates groups -Phosphoanhydride bonds
Nitrogenous base -A binds with T -C binds with G -RNA: A bind with U
Purines -Adenine -Guanine
Pyrimidines -Thymine -Uracil -Cytosime
Functions of Nucleotides -can act as an energy carrier -can bind with an enzyme to become a Coenzyme -can serve as an intracellular signaling molecules
NA in Coenzyme A -serves as a carrier of acetyl groups formed upon ozidative decarboxylation of pyruvate
NA in Cyclic AMP -binds to regulates function of protein kinases -Intracellular signaling molecules
NA in ATP -When NT acts as an energy carrier
DNA Structure -double helix -Deoxyribose as sugar -Thymine
RNA structure -single stranded -Ribose sugar -Urical replaces Thymine
Created by: Maddiestrat09
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