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Microbio Ch.6

QuestionAnswer
Why are acellular pathogens called so? Are they considered living? They are not composed of cells/ Not living
Understand the characteristics of viruses. (slide 2) DNA or RNA/ Capsid, envelope, or both/ Spikes/ Shapes: Helical, polyhedral, complex/ Needs to infect host to reproduce/ Acellular
What does it mean that viruses are obligate, intracellular parasites? Must infect a host to reproduce/ Narrow host range
What is meant by a "narrow host range?" Virus can either infect a human or a different species, but not both/ Not multiple different cells or organs
Define: capsid Always surrounded by a protein coat
Define: envelope Sometimes surrounded by a phospholipid membrane
What are the three main parts of a virus? DNA or RNA/ Capsid/ (Sometimes) Envelope
Define: naked virus Protein coat only
Define: enveloped virus. Contain capsid and envelope
What are spikes and why are they significant? Glycoprote9in extension of the capsid or envelope/ Attaches virus to other cells
How are viruses classified? What do ds and ss stand for? By the type of DNA or RNA found within the capsid of the virus// Single stranded virus
What do we mean when we say that viruses "hijack" host cells? Uses all of the hosts cell machinery to replicate
Understand the lytic cycle, including attachment The phage attaches to the surface of the host
Understand the lytic cycle, including penetration The viral DNA enters the host cell
Understand the lytic cycle, including biosynthesis Phage DNA replicates and phage proteins are made
Understand the lytic cycle, including maturation New phage particles are assmebled
Understand the lytic cycle, including lysis The cell lyses, releasing eh newly made phages
Understand the lysogenic cycle. What makes it different from the lytic cycle? Phage DNA incorporated into the host gnome/ Cells divide and prophage does too/ then the prophage enters the lytic cycle
What does temperate mean in relation to the lysogenic cycle? Becomes part of the hose cell chromosome/
Understand how viruses with animal hosts are different from bacteriophages 1-3 Attachment/ Penetration. Cell engulfs virus by endocytosis/ Uncoating
Understand how viruses with animal hosts are different from bacteriophages 4-6 Biosynthesis. Viral RNA enters nucleus, replicates by the viral RNA polymerase/ Assembly/ Release. the cell is not killed and continues to make new virus
What is uncoating? Viral contents are released by breaking envelope
Define different types of infections and examples of each: persistent Virus stays in certain tissues or organs of infected person// Herpes, Hepatitis C, HIV
Define different types of infections and examples of each: latent Virus stays hidden or dormant inside the cell// Chicken pox-Shingles
Define different types of infections and examples of each: chronic. Disease with symptoms that are recurrent or persistent over a long time// HIV
Understand the basics of viroids Short strand of circular RNA/ No protein coat
Understand the basics of prions. Infectious protein particle/ Caused by genetic mutation or spontaneously forms/ Responsible for transmissible spongiform encephalopathy. Ex. Kuru, Creutzfeldt-Jakob, and Mad Cow Disease
Created by: Clinton Perdue
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