click below
click below
Normal Size Small Size show me how
non- receptor mech.
pharmacology FRMB2612
| receptor mechanism | example |
|---|---|
| Drugs block ion channels | local anaesthetics, calcium channel blockers treatment for hypertension |
| Drugs enhance ion movement (neurotransmission) | antidepressants |
| Drugs inhibit enzymes | MAO - treatment for depression; COX - treatment for inflammation; ACE – treatment for hypertension; Carbonic anhydrase treatment for glaucoma |
| Drugs act by chemical reactions | antacids neutralise gastric acid |
| Drugs cause cytotoxic actions | anti-cancer drugs |
| Drugs inhibit DNA/RNA synthesis | antibiotics, anticancer drugs, antivirals |
| Drugs kill bacteria, fungi | antibiotics, anti-fungal drugs |
| Drugs act by physical properties | fiber laxatives |
| Drugs inhibit pumps in cell membrane | Na/K ATPase - treatment for heart failure; Proton pump – treatment for peptic ulcer |
| Drugs have Metal chelating agents | desferrioxamine binds to iron |