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VN140 Integ Pharm
| Question | Answer |
|---|---|
| ACNE PREPARATIONS | treat inflammatory diseases of the sebaceous glands and hair follicles of the skin |
| ACNE PREPARATIONS - drugs - benzoyl peroxide | Clearasil, Oxy 10 |
| ACNE PREPARATIONS - use | adjunctive treatment of mild to moderate acne vulgaris |
| ACNE PREPARATIONS - action | suppresses sebum. Also, slow release of oxygen exerts bacterialcidal action on the road shaped gram + Corynebacterium acne by oxidizing bacterial problem. |
| ACNE PREPARATIONS - side effect - minor | warmth, stinging, erythema |
| ACNE PREPARATIONS - side effect - major | allergic contact dermititis, edema |
| ACNE PREPARATIONS - nursing implication | wash thoroughly before applying. AVOID eyes in the mucus membrane. |
| ACNE PREPARATIONS - drugs - oral antibiotic | Tetracyclin |
| ACNE PREPARATIONS - drugs - Accutane | for acne not responding to oral antibiotic. |
| ANTI-PSORIATICS | prevents or relieves psoriasis |
| psoriasis | chronic skin disorder. Etiology is unknown. Red, scaly patches with silvery scales |
| ANTI-PSORIATICS - drug - methotrexate | Amethopterin (for severe psoriasis!) |
| ANTI-PSORIATICS - use | interferes with folic acid metabolism, inhibits DNA synthesis & cell reproduction |
| ANTI-PSORIATICS - side effect - minor | dizziness, drowsiness, h/a blurred vision |
| ANTI-PSORIATICS - side effect - major | pulmonary fibrosis, hepatotoxicity, N&V bone marrow suppression, nephropathy |
| ANTI-PSORIATICS - drug - other | Donovox (calcipotriene), baths (colloidal baths) |
| ANTISEBORRHEICS | counteracts or effectively treats seborrhea |
| seborrhea | disease of sebaceous glands with increased amt of fat, secretes red, yellow, white scaly crusted patches. Usually moist, greasy and itchy. SYMPTOMS: worse on cold months! |
| ANTISEBORRHEICS - drug - sulfacetamide sodium (Rx lotion) | sebicon (use on scalp!) |
| ANTISEBORRHEICS - action | bacteriostatic effect by interfering with bacterial use of PABA & inhibits folic acid biosynthesis needed for bacterial growth |
| ANTISEBORRHEICS - side effect - minor | temp burning/stinging sensation |
| ANTISEBORRHEICS - side effect - major | hypersensitivity (erythema, rash, pruritis) |
| ANTI-INFLAMMATORY (Topical corticosteroids) | hormones from cortex of the adrenal gland or they are prepared synthetically & they are used to relieve inflammation of skin |
| ANTI-INFLAMMATORY (Topical corticosteroids) FYI | never use topical steroid on skin when there is a known infection on the body (skin)! |
| ANTI-INFLAMMATORY (Topical corticosteroids) | medications come in: "low-mid-high potency" based on the particular steroid, conc, vehicle. Lotions, creams, gels & ointments are more potent due to increased absorption from these vehicle |
| ANTI-INFLAMMATORY (Topical corticosteroids) -drug - triamcinolone acetate | 0.025% Kenalog (low potency - good for long term treatments) |
| ANTI-INFLAMMATORY (Topical corticosteroids) -drug - fluocinolone acetonide | 0.025% Synalar (mid potency) |
| ANTI-INFLAMMATORY (Topical corticosteroids) -drug - betamethasone dipropionate | 0.05% Diprolene (high potency) |
| ANTI-INFLAMMATORY (Topical corticosteroids) - FYI | never use Fluorinated steroid on the face! |
| ANTI-INFLAMMATORY (Topical corticosteroids) - use | to relieve inflammatory manifestations of corticosteroid-responsive dematoses (psoriasis-dermatitis-eczema-insect bite reactions, 1st & 2nd degree sunburn) |
| ANTI-INFLAMMATORY (Topical corticosteroids) - action | exert localized anti-inflam. Reduce itching, redness, swelling |
| ANTI-INFLAMMATORY (Topical corticosteroids) - side effect - minor | skin irritation, burning, redness, swelling, itching |
| ANTI-INFLAMMATORY (Topical corticosteroids) - nursing implications | avoid cosmetics or bandages over site depending on the order - skin is washed w soap & water & applied to moist skin |
| BURN PREPARATIONS | reduce bacterial growth |
| BURN PREPARATIONS - drug - mafenide acetate | Sulfamylon (goes through eschar) |
| BURN PREPARATIONS - drug - silver sulfadiazene | silvadene (cream used to treat 2nd & 3rd degree burn to prevent infection |
| BURN PREPARATIONS - use | adjunctive therapy in 2nd & 3rd degree burtns for Tx & prevention of infection and possible sepsis |
| BURN PREPARATIONS - action | bacteriostatic against many organisms (ie Pseudomonas aeruginosa) |
| BURN PREPARATIONS - side effect - minor | Ay rxn is Important |
| BURN PREPARATIONS - side effect - major | intense pain, burning, rash, blisters, bleeding facial edema, etc |
| SCABICIDES | used to treat scabies |
| scabies | little mite that burrow under skin |
| SCABICIDES - drug - permethrin 5% (cream) | Elimite (Rx only) |
| SCABICIDES - action | scabicidal & anti pruretic |
| SCABICIDES - side effect - minor | feeling of warmth, slight skin irritation |
| SCABICIDES - side effect - major | tingling, numbness |
| SCABICIDES - nursing implication | pt should shower 1st, then w gloved hands massage into dry skin from head to soles of feet. Remove in 8-14 hrs by showering. If living mites after 14 d repeat process. Clothing & bed linen: wash separately in hot water twice. |
| PEDICULICIDES | used to kill lice |
| PEDICULICIDES - drug - permethrin 1% | NIX (OTC cream rinse) |
| PEDICULICIDES - action | causes paralysis of pest & inability to obtain burro into skin to obtain blood supply |
| PEDICULICIDES - side effect - minor | transient tingling & pruritis |
| PEDICULICIDES - side effect - major | burning, stinging, numbness, rash, edema |
| PEDICULICIDES - nursing implication | scalp as well as hair should be saturated w lotion. Leave in place for 10 mins. When hair is dry use fine tooth comb to remove dead lice. |
| CAUTERIZING AGENTS | used to destroy tissue. Do it with caustic cauterizing effect |
| CAUTERIZING AGENTS - drug - dichloroacetic acid | Bichloracetic Acid |
| CAUTERIZING AGENTS - uses | removal of warts |
| CAUTERIZING AGENTS - action | acids exert a keratolytic action which removes epidermal cells infected by viruses. |
| CAUTERIZING AGENTS - side effect | highly flammable, local irritation of normal skin |
| CAUTERIZING AGENTS - FYI | feet calluses, use SALICYLIC acid |
| CAUTERIZING AGENTS - nursing implication | avoid contact with eyes and mucous member. Do not apply to moles, birthmarks, warts on face or genital warts. |
| DEBRIDING AGENTS | liquefy necrotic tissue without effecting new or healthy tissue |
| DEBRIDING AGENTS - drugs- collagenase | Santyl |
| DEBRIDING AGENTS - use | debridement of necrotic (dead) tissue of severe burns or dermal ulcers |
| DEBRIDING AGENTS - action | enzymatic action digests peptide bonds of denatured & undenatured collagen, cellular & bacterial debris |
| DEBRIDING AGENTS - side effect | pain, redness, irritation, bacteremia |
| DEBRIDING AGENTS - nursing implications | avoid eyes, flush w copious amt of water before applic cleanse or flush with solution as ordered |
| TOPICAL ANTISEPTICS | inhibit the growth of microorganism |
| TOPICAL ANTISEPTICS - drug - | hydrogen peroxide |
| TOPICAL ANTISEPTICS - use | cleans wounds of dead tissue & pus |
| TOPICAL ANTISEPTICS - action | liberates oxygen to destroy anaerobic bacteria and effervescence loosens wound debris & pockets of bacteria |
| TOPICAL ANTISEPTICS - side effect | irritation of skin & mucous membrane |
| TOPICAL ANTISEPTICS - nursing implication | never instill h2O2 into a closed cavity or abscess where free 02 cannot escape. Notify physician if affected area is now pink granulation tissue w/o purulent d/c |
| TOPICAL ANTI-INFECTIVES | inhibit or DESTROY microorganism |
| TOPICAL ANTI-INFECTIVES - 3 types | topical antibiotics, antifungals, antivirals |
| TOPICAL ANTI-INFECTIVES - TOPICAL ANTIBIOTICS - drugs | bacitracin (baciquent), gentamicin (g-myticin) neomycin (myciguent) povidine (betadine) |
| TOPICAL ANTI-INFECTIVES - TOPICAL ANTIBIOTICS - use | to prevent superficial infections in minor cuts, wounds, abrasions, minor burns |
| TOPICAL ANTI-INFECTIVES - TOPICAL ANTIBIOTICS - action | either bactericidal or bacteriostatic: directly.ocally |
| TOPICAL ANTI-INFECTIVES - TOPICAL ANTIBIOTICS - side effect | contraindicated in pt's w known hypersensitivity. Use neomycin cautiously - can be toxic |
| TOPICAL ANTI-INFECTIVES - TOPICAL ANTIBIOTICS - nursing implications | assess wounds prior to admin. Note size, color & appearance. |
| TOPICAL ANTI-INFECTIVES - ANTIFUNGALS - drugs | miconazole (Micatin), econazole (Specetazole |
| TOPICAL ANTI-INFECTIVES - ANTIFUNGALS - drugs - Nystatin | treatment of antifungal in mouth especially w AIDS pts |
| TOPICAL ANTI-INFECTIVES - ANTIFUNGALS - use | tineacrutis, tineapedis, tinea corpus |
| TOPICAL ANTI-INFECTIVES - ANTIFUNGALS - action | kill (fungicidal) or stops growth of susceptible fungi by affecting the permeability of cell membr or protein synthesis w/in the fungi |
| TOPICAL ANTI-INFECTIVES - ANTIVIRALS - drug | acyclovir (Zovirax) & penciclovir (Denavir) |
| TOPICAL ANTI-INFECTIVES - ANTIVIRALS - use | to treat Herbes |
| TOPICAL ANTI-INFECTIVES - ANTIVIRALS - action | inhibits viral replication |
| ANTI-PRURITICS | prevents or relieves itching |
| ANTI-PRURITICS - drug - aluminum acetate soln. | Burrows solution |
| ANTI-PRURITICS - FYI | treament for poison ivy, mildly irritated skin, wet/open dressing |
| ANTI-PRURITICS - use | stop itching of mildly irritated inflamed skin |
| ANTI-PRURITICS - action | has anti-inflammatory, antipruritic, mild astringent, & antiseptic properies |
| SUNSCREENS | block skin absorption of various types of rays of the sun, depending on product used. |
| SUNSCREENS - UVA | (bad) penetrate deep into skin, they destroy the elasticity, they cause premature aging and contribute to skin cancer |
| SUNSCREENS - UVB | can cause unprotected skin to burn & thought to be the primary cause of skin cancer |
| SUNSCREENS - FYI | choose a sunscreen w at least SPF of 15. apply 15 mins prior to exposure. Re-apply after swimming, excercising or perspiring |
| THERAPEUTIC BATHS | emolient (softens and soothes) some are antipruritic |
| THERAPEUTIC BATHS - drug - colloidal oatmeal bath | Aveeno |
| THERAPEUTIC BATHS - use | to treat irritated skin, pruritis (chicken pox, poison ivy, etc) |
| THERAPEUTIC BATHS - action | soothes & reduces itching and irritation |
| oral troche | med to dissolve slowly in mouth |