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Antipsychotics FA

WVSOM -- First Aid -- Antipsychotics

Haloperidol neuroleptic
"-azines" neuroleptic
Olanzapine atypical antipsychotic
clozapine atypical
quetiapine atypical
risperidone atypical
aripiprazole atypical
ziprasidone atypical
neuroleptic moa block D2 receptors increasing cAMP
neuroleptic malignant syndrome rigidity, myoglobinuria, autonomic instability, hyperpyrexia
tardive dyskinesia oral-facial movements due to long-term antipsychotic use
Atypical antipsychotic MoA Block 5-HT2, alpha, H1 and dopamine receptor
atypical toxicity clozapine --> agranulocytosis; weight gain, fewer extrapyramidal than typicals
Lithium side effects nephrogenic DI, tremor, sedation, edema, heart block, hypothyroid, polyuria
Buspirone MoA stimulates 5-HT1a receptors
TCA MoA block reuptake and NE and serotonin
TCA toxicity 3 Cs: convulsion, coma, cardiotoxicity as well as confusion and hallucinations
Bedwetting imipramine
Imipramine TCA
amitriptyline TCA
desipramine TCA
nortriptyline TCA
clomipramine TCA
doxepin TCA
amoxapine TCA
Fluoxetine SSRI
paroxetine SSRI
sertaline SSRI
citalopram SSRI
Venlafaxine SNRI
duloxetine SNRI
SNRI MoA inhibit serotonin and NE
SSRI MoA serotonin-specific reuptake inhibitior
smoking cessation bupropion
bupropion moa increase NE and dopamine thru unknown mechanism
Mirtazapine alpha 2 antagonist (inc release of NE and serotonin)and potent 5-HT2 and 5--HT3 receptor antagonist
Maprotiline blocks NE reuptake
trazodone primarily inhibits serotonin reuptake. Used for insomnia.
MAOI MoA nonselective MAO inhibition --> increased levels of amine neurotransmitters
Phenelzine MAOI
tranylcypromine MAOI
isocarboxazid MAOI
selegiline MAO-B inhibitor
Created by: tjamrose