Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharmacology Step 1

QuestionAnswer
What drug is useful in an acute gouty attack? What is its MOA? Colchicine; binds to tubulin, blocks formation of microtubules and (-) phagocytosis of urate by WBCs
What is the MOA of Tiagabine? (-) GABA uptake by (-) GABA transporter
What is used in the tx of methanol ingestion? Fompeizole; inhibits alcohol dehydrogenase
What is used to reverse acute dystonias during antipsychotic tx? Benztropine; anticholinergic
What drug is a nonstimulant that inhibits reuptake of NE for the tx of ADHD? Atomoxetine
What is the MOA of Tacrolimus? binds to FKBP and inhibits calcineurin; prevents de-P of transcription factor NFATC
Which oral hypoglycemia causes a disulfram-like reaction? Chlorpropamide
How do cells acquire resistance to multiple anti-cancer drugs? MDR2 gene, cells overproduce cell surface glycoproteins
What is the MOA of Bleomycin? fragments DNA in G2 phase
Which anti-cancer drugs work by cross-linking DNA? alkylating agents (nitrosureas, cyclophosphamide)
How does cytarabine work ? pyrimidine antagonist; (-) chain elongation when AraCTP is incorporated into the chain
Which anti-canter drugs work by intercalating into DNA? doxorubicin, daunorubicin, dactinomycin
Which anti-cancer drugs can cause areflexia? vincristine, vinblastine
Which antidepressant blocks alpha2 receptors? Mirtazapine
How do you treat beta-blocker toxicity? glucagon
What is the MOA of metronidazole? bacterial/protozoal ferrodoxins reduce metronidazole to an active nitroderivative to (-) DNA replication and cause mutations
Which HIV drug causes redistribution of fat to central areas? protease inhibitors
What anti-cancer drugs work in the G2 phase? Bleomycin, Etoposide
Created by: ash0403