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Shawnee Spring 2006
| Drugs | Side Effects |
|---|---|
| Salicylates | GI irritation (dyspepsia, nausea, ulcer, hemorrhage); Prolonged bleeding time Exacerbation of asthma (aspirin-sensitive asthma) Tinnitus, dizziness with repeated large doses |
| NSAIDS | GI irritation (dyspepsia, nausea, ulcer, hemorrhage) Prolonged bleeding time Headache, tinnitus Rash Acute renal insufficiency and other renal mudullary changes Exacerbation of asthma (cross-reactivity with aspirin) |
| Nonopioid Analgesics (Tylenol, Zostrix) | Rash, urticaria Hepatoxicity (especially in presence of alcohol abuse) Leukopenia Localized burning sensation, erythema |
| Nonopioid Analgesics ( Ultram) | GI irritation (dyspepsia, nausea, ulcer, hemorrhage) Dizziness, headache Somnolence Pruritus |
| Opioid Analgesics | GI irritation (dyspepsia, nausea/vomiting, constipation) Dizziness, headache, orthostatic hypotension Sedation, respiratory depression |
| Corticosteroids (Intraarticular Injections) | Local osteoporosis, tendon rupture, neuropathic arthropathy from frequent injection. Dermal/subdermal changes leading to depression at injection site Possibility of local infection |
| Corticosteroids (Systemic) | Cushing syndrome (including fluid retention), GI irritation, osteoporosis, insomnia, hypertension, steroid psychosis, diabetes mellitus, acne, menstrual irregularities, hirsutism, risk of antibiotic-resistant infection, brusing. |
| DMARDs (Rheumatrex) | Hepatotoxicity occurs more often with frequent sm doses than with large intermittent doses. Sm dose & different administration scdl for RA make it less likely that pt will develop symptoms related to drug's antineoplastic activity (bone marrow depresion) |
| DMARSs (Azulfidine, Salazopyrin) | GI effects (anorexia, N/V), Bleeding bruising, jaundice, Headache, rash, urticaria, pruritus |
| DMARDs (Arava) | Nausea, diarrhea, Respiratory tract infection, alopecia, Rash |
| DMARDs (penicillamine) | GI irritation (N/V, anorexia, diarrhea) reduced altered taste. Rash, hematuria. Iron deficiency (esp. in menstruating women) |
| DMARDs (Gold Compounds) | Decreased hemoglobin, leukopenia, thrombycytopenia, Proteinuria, hematuria. Stomatitis |
| DMARDs (Antimalarials) | Ocular toxicity (retinopathy) may progress even after drug is discontinued, Ototoxicity. Peripheral neuritis, neuromyopathy, pypotension, electrocardiogram changes with prolonged therapy. |
| Immunosuppressants | GI irritation (N/V), anorexia with large doses). Rash |
| Biologic Therapy (Enbrel) | Injection site reaction including erythema, pain, itching, swelling. Abdomial pain, vomiting. Dizziness, headache. Rhinitis, pharyngitis, cough. |
| Biologic Therapy (Remicade, Humira, Kineret) | Abd pain, N/V. Dizziness, headache. Rhinitis, cough, sinusitis, pharyngitis. Injection site reaction. Leukopenia, headache. Abd pain, rash. |
| Antibiotics | GI effects (N/V, diarrhea, stomach cramps). Dizziness. Photosensitivity (severe) |
Created by:
nancypack
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