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Micro - Ch 8
| Question | Answer |
|---|---|
| Genetics | The study of inheritance and heritable traits as expressed in an organism's genetic material. |
| Genome | The sum of all the genetic material in a cell or virus. |
| Chromosome` | A molecule of DNA associated with protein. In prokaryotes, typically circular and localized in a region of the cytosol called the nucleoid. In eukaryotes, chromosomes are threadlike and are most visible during mitosis and meiosis. |
| Gene | A specific sequence of nucleotides that codes for a polypeptide or an RNA molecule. |
| DNA | Nucleic acid consisting of nucleotides made up of phosphate, a deoxyribose pentose sugar, and an arrangement of the bases adenine, guanine, cytosine, and thymine. |
| Genetic Code | The mRNA condons and the amino acids they encode. |
| Phenotype | The physical features and functional traits of an organism expressed by genes in the genotype. |
| Transcription | Process in which the genetic code from DNA is copied as RNA nucleotide sequences. |
| Translation | Process in which the sequence of genetic information carried by mRNA is used by ribosomes to construct polypeptides with specific amino acid sequences. |
| Condons | Triplet of mRNA nucleotides that codes for specific amino acids. For example, AAA is a codon for lysine. |
| Mutation | In genetics, a change in the nucleotide base sequence of a genome. |
| Base substitution | The replacement of a single base in DNA by another base, causing a mutation; also called point of mutation |
| Missense mutation | A substitution in a nucleotide sequence resulting in a codon that specifies a different amino acid: what is transcribed makes sense, but not the right sense. |
| Nonsense mutation | A substitution in a nucleotide sequence that causes an amino acid codon to be replaced by a stop codon. |
| Frameshift mutation | Type of mutation in which nucleotide triplets subsequent to an insertion or deletion are displaced, creating new sequences of codons that result in vastly altered polypeptide sequences. |
| Spontaneous mutation | A mutation that occurs without a mutagen |
| Mutagen | Physical or chemical agent that introduces a mutation that changes the microbe's phenotype. |
| Transformation | Method of horizontal gene transfer in which a recipient cell takes up DNA from the environment. |
| Conjugation | In genetics: method of horizontal gene transfer in which a bacterium containing a fertility plasmid forms a conjugation pilus that attaches and transfers plasmid genes to a recipient; in reproduction of ciliates: coupling of mating cells. |
| Transduction | Method of horizontal gene transfer in which DNA is transferred from one cell to another via a replicating virus. |
| Plasmid | A small, circular molecule of DNA that replicates independently of the chromosome. Each carries genes for its own replication and often for one or more nonessential functions such as resistance to antibiotics. |
| R factors | A bacterial plasmid carrying genes for replication and conjugation for antibiotic. |