click below
click below
Normal Size Small Size show me how
Autoantibodies
| Question | Answer |
|---|---|
| Antinuclear antibodies (ANA) | SLE |
| Anti-dsDNA, anti-Smith | Specific for SLE (anti-Smith are most specific) |
| Antihistone | Drug-induced lupus |
| Anti-IgG | Rheumatoid arthritis (known as Rheumatoid factor) |
| Anticentromere | Scleroderma (CREST) |
| Anti-Scl-70 (anti-DNA topoisomerase I) | Scleroderma (diffuse) |
| Antimitochondrial | Primary biliary cirrhosis |
| Antigliadin, antiendomysial | Celiac Disease |
| Anti-Basement membrane | Goodpasture's |
| Anti-desmoglein | Phemigus vulgaris |
| Antimicrosomal, antithyroglobulin | Hashimoto's thyroiditis |
| Anti-Jo-1 | Polymyositis, dermatomyositis |
| Anti-SS-A (anti-RO) | Sjogren's syndrome |
| Anti-SS-B (anti-La) | Sjogren's syndrome |
| Anti-U1 RNP (ribonucleoprotein) | Mixed connective tissue dz |
| Anti-smooth muscle | Autoimmune hepatitis |
| Anti-glutamate decarboxylase | Type I diabetes mellitus |
| c-ANCA | Wegener's granulomatosis |
| p-ANCA | Microscopic polyangitis (form of polyarteritis nodosa) |
| The three vasculitides associated with antineutrophil cytoplasmic antibodies (ANCA) | Wegener's granulomatosis, Microscopic polyangitis, & Churg-Strauss syndrome |