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DNA
Identifying the Substance of Genes
| Question | Answer |
|---|---|
| In 1923, _________ ________ experimented with mice, bacteria, and pneumonia. He termed his experiment ______________ because the ability to cause disease was inherited by the mice offspring. | Frederick Griffith; transformation |
| In 1944, ______ _____ observed bacterial transformation, and discovered that the nucleic acids DNA stores and transmits genetic information from one generation to the next. | Oswald Avery |
| What is bacteriophage(phage)? | a kind of virus that infects and replicates within bacteria |
| _______ and _____ conducted an experiment with bacteriophages that confirmed Oswald Avery's results, convincing many scientists that DNA was the genetic material found in genes, not just in viruses and bacteria, but all living cells. | Hershey; Chase |
| What must the DNA that makes up genes be capable of? | storing, copying, and transmitting the genetic information |
| What is DNA? | a nucleic acid made up of nucleotides joined into long strands or chains by covalent bonds |
| What are chromosomes? | coiled up strands of DNA |
| Where are chromosomes found in eukaryotic cells? | the nucleus of the cell |
| What is DNA made of? | many small sections called nucleotides |
| What does DNA stand for? | deoxyribonucleic acid |
| When does DNA copy itself? | during the S section of interphase |
| DNA is made of _ long strands of nucleotides. | 2 |
| What are the 3 parts of nucleotides? | deoxyribose(sugar), phosphate group, and nitrogen base |
| What are the four different nitrogenous bases? | adenine, thymine, guanine, cytosine |
| What shape is DNA? | a twisted ladder or a double helix |
| Who was the double helix shape discovered by? | Watson and Crick, with the help of Rosalind Franklin |
| What are the "rungs" of the DNA shape? | nitrogenous base pairs, held together by hydrogen bonds |
| Adenine will always bond with _______, while Cytosine will always bond with _______. | Thymine; Guanine |
| What are the sides of the "ladder", or the backbone? | alternating deoxyribose and phosphate units |
| Each twist of the DNA molecule has __ base pairs. | 10 |
| The sides of the "ladder" of DNA are called ____________ because the sequence of the bases on one strand is an exact compliment to the bases on the other. | complimentary |
| How does the sequence of DNA replication start? | an enzyme called DNA helicase "unzips" the 2 strands at the base pairs(hydrogen bonds break) |
| What is DNA polymerase? | an enzyme that joins individual nucleotides to produce a new strand of nucleotides during DNA replication |
| What is DNA found at the tips of chromosomes called? | telomeres |
| Replication in most ___________ cells starts from a single point and proceeds in two directions until the entire chromosomes is copied. | prokaryotic |
| In __________ cells, replication may begin at dozens or even hundreds of places in the DNA molecule, proceeding in both directions until each chromosomes is completely copied. | eukaryotic |
| All enzymes are ________. | proteins |
| What is a codon? | a trinucleotide sequence of DNA or RNA that corresponds to a specific amino acid |
| What is an okazaki fragment? | short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication |