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nerve impulse
| Question | Answer |
|---|---|
| resting | Na VGCP - close Na ions - no move (outside) K VGCP - close K ions - no move (inside) |
| reaching threshold | Na VGCP - closed Na ions - some enter thru pump K VGCP - close K ions - no move (inside) |
| depolarisation | Na VGCP - open Na ions - move in K VGCP - closed K ions - stays in |
| repolarisation | Na VGCP - closed Na ions - no move/pumped out K VGCP - open K ions - move out |
| hyperpolarisation | Na VGCP - close Na ions - no move/pumped out K VGCP - close K ions - pumped in |
| 1 | nerve impulse reaches axon terminal of presynaptic neuron |
| 2 | Ca2+ ions move in thru Ca2+ voltage gated channel proteins (originally out) vesicle containing neurotransmitter move toward membrane |
| 3 | vesicle fuse with membrane and releases neurotransmitter via exocytosis |
| 4 | neurotransmitter molecule diffuse across synaptic cleft along concentration gradient |
| 5 | neurotransmitter binds with specific receptor & activates new impulse |
| 6 | neurotransmitter in cleft is reabsorbed/transported & enzyme break down neurotransmitter on receptor (clearance) |