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OB/GYN

STEP 2 UWORLD

QuestionAnswer
What are contraindications in patients with placenta previa? No digital cervical examination and no intercourse
What is the possible consequence of cervical manipulation in patients with Placenta Previa? Severe painless hemorrhage
What is typically the 1st manifestation of female puberty? Breast bud development
How long after breast bud development is a female expected to have menarche? 2-2.5 years
Menarche and puberty should be achieved by what age? <15 years old
When levothyroxine should be ↑ in hypothyroid pregnant women? Now she knows about her current preganacy
What is the treatment option for Vulvar Lichen Sclerosis? Clobetasol (high potency topical steroid)
How is vulvar lichen sclerosis presented? Pre-pubertal girls with intense pruritis and thin, white lesions of the vulva and peiranal region
At what point (weeks) are all pregnat women screened for gestational diabetes? 24-28 weeks
What are R/Fs that intitle a woman to be screen earlier for gestational diabetes? Obesity and Hispanic heritage
What is tocolysis? Inhibition of contractions
What are risks/effects of using Indomethacin in a pregnant woman? Oligohydramnios and premature closure of PDA
At what point (gestational age) does the benefits of Indomethacin use outweigh the risks? Preterm labor at <32 weeks
Infertility in woman >35 years old. Failure to conceive in 6 months of unprotected sex
What is used to diagnose an anatomic issue leading to infertility in a woman? Hysterosalpingogram
What are the criteria for diagnosing recurrent UTI? 2 or more infections in 6 months, or 3 more infections in 1 year
What are preventive measures for recurrent UTIs? 1. Behavior modification 2. Postcoital or daily antibiotic prophylaxis 3. Topical vaginal estrogen for post-MP women
What is the NBSM in post-MP women with endometrial polyps? Hysteroscopic polypectomy for adequate evaluation of endometrial hyperplasia/cancer
How does tobacco smoking affect endometrial cancer? Reduces the chances of endometrial cancer
What is the main R/F for endometrial cancer? Excessive uterine estrogen exposure (MC obesity, chronic anovulation)
Gout and which genitourinary condition are decreased by smoking? Endometrial cancer
When is the antennal GBS screening done? Rectovaginal culture at 36-38 wk. gestation
What are the indications for GBS intrapartum prophylaxis? 1. GBS bacteriuria or GBS UTI in current pregnancy 2. GBS (+) rectovaginal culture in current pregnancy 3. Unknown GBS status + any of the following: a) <37 wk. gestation b) Intrapartum fever c) Rupture of membranes > or equal 18 hrs. 4. Prior infant with early-onset neonatal GBS infection
What antibiotic is used for GBS prophylaxis? IV penicillin
What is the workup in patient with low/average risk for Ovarian cancer? No screening necessary
What is the main stratification for ovarian cancer screening? Family HX for Ovarian cancer
How is Pelvic Organ prolapse? Pelvic pressure, urinary retention, incontinent, and obstructed voiding.
What are common R/Fs for Pelvic Organ prolapse? Multiparity, post-MP age, hysterectomy, and obesity
What is the definition of labor? Painful, regular contraction that causes cervical change
What is "false" labor? Mildly painful, irregular contractions with no cervical change
What is the infectious cause of chorioamnionitis? Polymicrobial
What is the best TX for Chorioamnionitis? Broad-spectrum IV antibiotics and expedited delivery to ↓ neonatal and maternal morbidity
What is the best form to minimize risk of errors in cases of hierarchy-based barriers? Teamwork and safety culture interventions
How are symptomatic fibroids clinically described? Associated with heavy periods and an enlarged uterus with irregular contour
When is surgery indicated for uterine fibroids? Only in symptomatic patients that are done having kids
Urinary incontinence due to pre-labor or rupture of the uterine membrane will have fluid that will test: Nitrazine and Fern negative testing
What is the most accurate 1st trimester measurement for Estimated Gestational Age (EGA)? U/S dating with fetal crown-rump measurement
Which trimester is the only one in which the EGA can be modified to adjust for discrepancies? 1st trimester only
What is the most important risk factor for uterine rupture? Prior uterine surgery, especially a previous C-section.
What are minor risk factors for Uterine rupture? 1. Short interpregnancy interval (<6-18months) 2. Maternal age >35
How is Uterine rupture clinically presented? Sudden onset of abdominal pain, vaginal bleeding, fetal decelerations, and an irregular abdominal mass
What is the irregular mass(es) seen or felt in Uterine rupture? Protruding fetal parts
What is the overall MCC of abruption placentae? Vasoconstriction
What is abruptio placenta? Premature placental separation from the uterus
What is prophylaxis TX for pre-eclampsia? Low-dose aspirin
What is the time range to administer pre-eclampsia prophylaxis? 12-28 wks., but best if given before 16wk.
What would be the best way to adapt and prevent errors in clinical emergencies, such as McRoberts maneuver, in a hospital setting? Simulation-based training
What is the next step in management in a pregnant patient with a Pap smear demonstrating high grade squamous intraepithelial lesions? Immediate colposcopy
What is Pseudocyesis? Persistent, non-delusional belief of being pregnant
What are S/S seen with Pseudocyesis? Symptoms of early pregnancy such as morning sickness and abdominal distension.
How is Pseudocyesis diagnosed over true pregnancy? Pregnancy test is negative and U/S reveals and empty uterus
What is the finding of an empty uterus on ultrasound? Thin endometrial stripe
What is MCC of 1st trimester fetal growth restriction? Chromosomal anomalies
What is the 2nd MCC of 1st trimester fetal growth restriction? Torches infections
How is magnesium-sulfate toxicity clinically presented? Absent patellar reflex, respiratory depression/paralysis, and cardiac arrest.
What is the treatment for Magnesium-sulfate toxicity? Calcium gluconate
Thin endometrial stripe indicates --> Empty uterus
What is the best test to DX uterine fibroids? Pelvic ultrasound
What is the most significant risk factor for breast cancer? ↑age
What are minor risk factors for breast cancer? ↑estrogen exposure, family HX (BRCA1/2)
What are clinical manifestations that indicate possible breast cancer? Skin changes (peau d'orange), nipple d/c, axillary lymphadenopathy, palpable (nontender) breast mass, and abnormal mammogram
What is NBSM in post-MP woman with vaginal bleeding persistent despite use of OCPs? Endometrial BX to check for hyperplasia/cancer.
What is the role or use for the Progesterone withdrawal test? Evaluate secondary amenorrhea in case it is due to low estrogen.
How is secondary amenorrhea defined? No menses >6 months in pts w/ previous irregular menses
What is another name for Mullerian Agenesis? Mayer-Rokitansky-Kuster-Hauser syndrome
What test is often recommended in a patient with Mullerian agenesis? Renal ultrasound
Why is a renal U/S often required in Mullerian Agenesis patient? The urogenital development and the development of the uterus, cervix, and upper 1/3 of vagina, share a common embryologic source
What is a common complication of PID? Tuboovarian abscess
How is tuboovarian abscess described clinically? Fever, diffuse abdominal pain that gradually worsens on one side, and both uterine and adnexal tenderness
What the U/S findings in a tuboovarian abscess caused by PID? Complex multiloculated adnexal mass with thick walls and internal debris
Common contraindication, related to blood pressure, for use of OCPs? Patients with HTN, and those who develop hypertension takin OCs should discontinue the medication
What is an adverse effect to a Cold Knife Conization? Deleterious effects on future pregnancy
What and when is Cryosurgery used in cervical cancer? Liquid nitrogen treatment for High-grade Squamous Intraepithelial lesions in diagnosed patients
What is the normal menstrual cycle (according to RX and First aid)? 21-35 days
How can ovulation day be calculated? X (cycle time) - 14
What histological description indicates endometrial cancer? Small, rough, regular glands growing in confluent pattens back-to-back glandular tissue without connective tissue in btw
What is the main etiology for development of endometrial cancer? Unopposed estrogen exposure over a prolonged period of time
What hormonal elevated levels are almost pathognomonic for premature ovarian failure? High FSH and LH
How is POF and Complete insensitivity syndrome different? Estrogen is expected elevated in Complete insensitivity syndrome
What is checked in a man for infertility? Semen analysis
What are the labs or tests done to diagnose infertility in a woman? Hormonal profile, pelvic ultrasound and hysterosalpingogram
What are protective measures for endometrial cancer development? Combined OCPs, late menarche, early menopause, and multiparity
What is the surgical treatment for localized endometrial cancer? Total hysterectomy with bilateral salpingo-oophrorectomy
Unilateral bloody nipple discharge with normal imaging and normal physical exam and breast size. DX? Benign intraductal papilloma
What is the NBSM for intraductal papilloma? Surgical duct excision and complete removal of any identified tumor
How is the discharge of candida vulvovaginitis described? Thick, curdy, white adherent to walls of vagina
What is the treatment of choice for candidal vaginitis? PO fluconazole
What is the best or most definitive test to DX endometriosis? Direct visualization (±bx) of ectopic endometrial tissue via laparoscopy
What is a contradiction for a Copper IUD? Setting of active infection or a HX of pelvic infection in the last 3 weeks.
How does Levonorgestrel prevent pregancy? Prevents/delay ovulation by preventing egg fertilization by affecting the cervical mucus and/or ability of sperm to bind to egg.
What is the Yuzpe method? cOCPs taken in doses; Progestin + Estrogen 1st dose as soon as possible, w/ 2nd dose 12 hrs. later.
MOA of Copper IUD: Prevents fertilization by causing chemical change in sperm and egg before they can meet.
What is the cause of primary dysmenorrhea? Excess production of prostaglandins in the endometrium
Created by: rakomi
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