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Bio Chapter 8
Question | Answer |
---|---|
what types of genes within genetic mutations can cause cancer to develop? | Oncogenes and tumor suppressor genes |
The best description of mitosis is the type of cell division that separates chromosomes and produces _ _ _ with ______ nuclei. | two daughter cells, identical |
the time between cell divisions in which DNA replication, basic cellular activities, and cell growth take place is called _________ | Interphase |
A single molecule of DNA and its associated proteins is called a(n) | Chromosome |
Place the phases of mitosis in the order that they occur, beginning with the first phase at the top. | 1. prophase 2. prometaphase 3. metaphase 4. anaphase 5. telophase |
What occurs during prophase? | -centrosomes migrate to opposite poles. - chromosomes condense - mitotic spindle begins to form |
Cancer cells are characterized by: | uncontrolled cell division |
What must occur before DNA polymerase can synthesize new DNA? | -the double-stranded DNA is unwounded -an RNA primer is added |
The _________ is a small section of a replicated chromosome that attaches sister chromatids to each other. | Centromere |
A stretch of DNA wrapped around proteins; become tightly arrayed during chromatin condensation. | Nucleosome |
In many types of cancer, mutations have converted photo-oncogenes to _____________ or have inactivated other genes called _____________ genes. | oncogenes; tumor supressor |
_______ are proteins around which DNA winds. | Histones |
a ______ is a replicated copy of a chromosome. | Chromatid |
What are some are components of chromatin? | -proteins for transcription -proteins for replication -DNA -proteins for scaffolding |
What checkpoint monitors the cell's supply of DNA nucleotides during DNA replication? | "S" checkpoint |
After eukaryotic DNA replication, what happens to the nucleosomes in chromatins? | they fold and wind into a compact form. |
In order for cancer to form, usually _________ of a tumor suppressor gene must be mutated. | both copies |
Which of the following that describe the products of one cell undergoing mitotic cell division? | -2 daughter cells -organelles distributed to daughter cells |
During pro metaphase, spindle fibers attach to proteins called _________ that assemble at each centromere of a chromosome. | kinotochores |
Select all of the processes that are due to mitotic cell division. | - repair after injury -growth of a zygote into a multicellular adult -replacement of lost cells |
What phases that occur within interphase of the cell cycle? | -S -G0 -G1 -G2 |
The contractile ring of protein filaments at the tip of this arrow forms an indentation called the _________ furrow, which helps divide the cytoplasm of an animal cell in a process called ______________. | cleavage; cytokinesis |
The cell cycle has internal _____________ that do not let the cell proceed to the next stage of the cell cycle until the previous stage is complete. | Checkpoints |
In ____________, the mitotic spindle disassembles and division of the genetic material is complete, but the cell cytoplasm has not yet divided. | Telophase |
The last cell cycle checkpoint prior to the initiation of mitosis is called the ________ checkpoint. | G2 |
Select all of the following that are true about growth factors triggering cell division. | -growth factors bind receptors on the cell membrane. -in response to a signal, a cascade of chemical reactions inside the cell initiates cell division. -a growth factor stimulates the production of new skin cells at a wound site. |
_________ ____________: block the recruitment of blood vessels by a tumor. | angiogenesis inhibitors |
During the _______ phase of interphase, DNA replication occurs. | S |
What enzyme has proofreading and repair functions during DNA replication? | DNA polymerase |
Select all of the reasons that cells need to control their rate of division. | -uncontrolled cell division can lead to abnormal growth -too little cell growth will not allow injuries to be repaired. |
Select the true statements that describe cancer cells compared to normal cells. | - cancer cells may have multiple nuclei. -cancer cells are less specialized than normal cells. |
The nuclear envelope breaks down during what phase of mitosis? | prometaphase |
The enzyme called DNA __________ adds new complementary DNA nucleotides to a single-stranded DNA template. | Polymerase |
_________ is a specialized type of cell division that produces cells that are genetically different from each other. | Meiosis |
Select all of the following that are true about photo-oncogenes. | -when they are overactive because of mutation, the cell cycle may become accelerated. - they encode proteins that stimulate cell division. |
Select all of the following that are true with respect to the G1 checkpoint. | - it promotes the expression of DNA damage repair enzymes -it screens for DNA damage - it can promote apoptosis if the DNA damage is too severe. |
Proteins called _________ are chemical signals that bind to receptors on a cell membrane and trigger cell division. | Growth factors |
Adults produce haploid _________ through the process of ________. | gametes, meiosis |
Arrange the terms on the left in order from largest to smallest in a eukaryotic organism. chromatid, nucleosome, nucleotide, replicated chromosome, cell, histone | cell, replicated chromosome, chromatid, nucleosome, histone, nucleotide; |
Centromeres split during what phase of mitosis? | Anaphase |
DNA replication initiates at specific points, called ______, where the DNA double helix is unwound. | Origins |
This enzyme forms covalent bonds between adjacent DNA segments. | DNA ligases |
This strand is synthesized during DNA replication. | Daughter Strand |
True or False: The component of DNA nucleotides that varies to produce organisms DNA is deoxyribose | False |
____ __________ is the process by which DNA is reproduced with the use of associated enzymes | DNA replication |
What are the building blocks of nucleic acids? | Nucleotides |
What is the enzyme that builds a short complementary strand piece of RNA? | Primase |
How many chromosomes are in the human heart? | 46 chromosomes |
Why does a replication form have a leading and lagging strand? | Replication can only occur in a 5' to 3' direction |
What is the role of telomerase? | allows for telomere length and equilibrium by adding on repeats to the end of the chromosome |
In eukaryotic cells, if you compared the DNA sequence of a gene with the sequence of the processed mRNA that was transcribed from the gene, you would find that ____ ______ ___________ | the mRNA is shorter because it does not contain introns |