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HEMOTOLOGY
CCRN
| Question | Answer | Rational |
|---|---|---|
| AIDS-related complex (ARC) | A phase of infection with HIV | |
| Pneumonia | The major cause of death in AIDS | Usually caused by the protozoa Pneumocystis carinii or cytomegalovirus (CMV) |
| KAPOSI'S sarcoma and Lymphoma | Common cancers of AIDS | |
| (ELISA) ENZYME-LINKED IMMUNOSORBENT ASSAY | SCREENING TESTS FOR AIDS | USUALLY IT TAKES 4 -12 WEEKS SINCE INFECTION FOR A POSITIVE TEST. |
| Western blot test | screening tests for AIDS | |
| HAART regime (highly active antiretroviral therapy) | It combines three or more anti-HIV medications in a daily dosing program. | |
| Nucleotide reverse transcriptase inhibitors (NRTIs) | These drugs are used to prevent healthy T cells in the body from becoming infected with HIV. | When HIV uses an NRTI instead of a normal building block, reproduction of the virus is stalled. |
| Nonnucleoside reverse transcriptase inhibitors (NNRTIs) | These drugs attache themselves to reverse transcriptase and prevent the enzyme from converting RNA to DNA. | The genetic material of HIV cannot be incorporated into the healthy genetic material of the cell. |
| Protease inhibitors (PIs) | These inhibitors are designed to attack HIV by blocking an enzyme crucial to the virus's reproduction. | It cripples the virus's ablility to replicate itself. |
| Fusion inhibitors | These drugs work by blocking HIV entry into the cells. | The newest class of drugs; ENFUVIRTIDE. |
| Hodgkin's Disease | A chronic, progressive neoplastic disorder of unknown cause. | Characterized by enlargement of lymph glands, spleen, and liver. |
| Leukemia | A group of malignancies caused by abnormal reproduction of white blood cells. | The useless, immature cells called blasts. |
| Acute lymphocytic Leukemia | The most common type of leukemia under age of 19 | It is the infiltration and accumulation of immature lymphoblasts. |
| MULTIPLE MYELOMA | A neoplasm of the bone marrow that is rapidly fatal. | 1. Pt. present with backache and bone pain.2. diruption of erythrocytes, leukocytes and thrombocytes. 3. Urine contains Bence Jones protein. |
| 1 unit of PRBC should increase Hgb and Hct by how much? | hemoglobin by 1g/DL and hematocrit by 3% | |
| AIDS | Infectious disease caused by human T-cell lymphotrophic Type III virus. | The AIDS virus zeros in on certain T lymphocytes and breads down the immunity |
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nerdismart
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