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Cell Cycle & Mitosis
| Term | Definition |
|---|---|
| Where is DNA located in a normal eukaryotic cell? | In the nucleus |
| Chromatin | A loose combination of DNA and proteins; the phase DNA is in during much of the cell cycle; the "noodle" stage |
| How many chromosomes are located in a human somatic cell? | 46 |
| Where is DNA located in a prokaryotic cell? | In the cytoplasm |
| Gene | A specific sequence of nucleotides that codes for a protein |
| Centromere | The region of a chromosome where chromatids are held together |
| What is the name of a sex cell in humans? | gamete (sperm and egg) |
| Autosome | A chromosome that is not a sex chromosome. |
| What is a karyotype? | A display of an individual's chromosomes in order of size |
| Haploid | Half the usual number of copies of each chromosome, based on a somatic cell of the species |
| Diploid | Two copies of each chromosome |
| How do prokaryotes (bacteria) perform cell division? | Binary fission |
| What are the two forms of cell division in eukaryotes (ex: humans) called? | Mitosis and meiosis |
| What is mitosis? | Division of the nucleus |
| What is cytokinesis? | Division of the cytoplasm |
| About 90% of the cell cycle, including the stages of G1, G2, and S stage is called? | Interphase |
| What happens in G1? | Majority of growth |
| What happens during the S phase? | Synthesis or replication of the DNA |
| What happens during G2? | More growth and replication of cell parts, DNA error checking, and preparing for cell division |
| What happens during Prophase? | chromatin fibers coil tightly into visible chromosomes, nuclear membrane begins to disappear, centrioles begin to move to opposite ends of the cell, and spindle fibers begin to form |
| What happens during Metaphase? | Spindle fibers attach to the centromeres of chromosomes and move the chromosomes to the middle of the cell |
| What happens during Anaphase? | Sister chromatids are pulled by spindle fibers to opposite poles of the cell, and each new chromosome has identical genetic information |
| What happens during Telophase? | Nuclear membranes form around each cell's set of chromosomes, the chromosomes begin to uncoil into chromatin, nucleoli reappear, and a cleavage furrow starts to form in the cytoplasm (of animal cells) as the cell prepares to divide. |
| cancer | Uncontrollable cell division due to internal controls being damaged from environmental conditions or possible mutations. A disorder of the cell cyle. |
| metastasis | When cancer spreads to other parts of the body - usually through the blood stream |
| Where does a "cell plate" form? | In plant cells during telophase |
| cell cycle | A series of events that cells go through as they grow and divide |
| Centriole | A cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division. |
| Cleavage furrow | The indentation that occurs in the middle of an animal cell that is ready to complete cytokinesis. |
| Chromatid | One half of a chromosome |
| Somatic | Any body cell except for reproductive cells. |
| Sister chromatid | chromatids that are identical |
| Telomere | A structure of repeating nucleotides at the end of DNA molecules that helps prevent the loss of genes during DNA replication and cell division. |
| Chromosome | A continuous thread of DNA containing genes and regulatory information; the stage DNA is in when packaged for "moving" - cell division |
| Histone | A protein that DNA wraps around; helps package DNA and provide structural support for chromosomes |
| Sex chromosome | A chromosome that determines biological sex. In humans, X and Y. |
| What happens in G0? (G zero) | Cell cycle arrest. The cell remains in interphase and does not continue to the S phase. |
| Differentiation | The process by which unspecialized or less-specialized cells acquire specialized structures and functions. |
| Development | The series of changes organisms undergo in their passage from the embryonic state to maturity, from a lower to a higher state of organization. |