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Unit 5 Biology

Biology

QuestionAnswer
What are the three parts of the monomer? Phosphate groups, Ribose (sugar), and Nitrogenous base (adenine)
What parts of the monomer make up the backbone of the DNA molecule? Phosphate groups and deoxyribose sugars
What type of bond holds the complementary bases together? Is it a strong or weak bond? Hydrogen bond, its weak
Anti-parallel: Running in opposite directions
Chargaff's Rule: [C] = [G] and [A] = [T] for any length of DNA.
What is the purpose of replication? Purpose: To produce two identical copies of a DNA molecule.
Helicase: Removes the RNA Primers
Primase: Adds RNA Primer
DNA Polymerase: Builds an Okazaki Fragment in 5' to 3' direction.
DNA Ligase: Joins the Okazaki Fragments together.
Which part of the cell cycle does DNA Replication take place? Interphase, S Phase
Central Dogma: DNA -------------RNA --------------Protein Transcription Translation
Transcription: Synthesis of an RNA molecule from a DNA template
Translation: The process whereby genetic information coded in messenger RNA directs the formation of a specific protein at ribosomes in the cytoplasm (making protein from mRNA)
Where does Transcription take place? Nucleus
Where does Translation take place? Cytoplasm
What is the role of tRNA in protein synthesis? Carries amino acids from the cell to the ribosome.
What is the role of rRNA in protein synthesis? Together with other proteins makes up the ribosome.
Silent: Mutated codon codes for the same amino acid
Missense: Mutated codon codes for a different amino acid
Nonsense: Mutated codon is a premature stop codon
Insertion: Extra nucleotide is added to the sequence
Deletion: Deletion –
Primary (1) amino acid sequence; this determines the next 3 levels
Secondary (2) the amino acid chain coils and folds into spirals or sheets due to Hydrogen Bonds
Tertiary (3) the (2) structure folds on itself
Quaternary (4) one or more polypeptide chains are added; a.k.a. globular protein; hemoglobin is an example.
Active site: place on the enzyme where the work occurs. It is substrate specific
Denature: To lose shape
What would cause an enzyme to denature? Extreme temperatures or changes in pH
Why must the lagging strand be built in segments? What are these segments called? DNA is antiparallel and polymerase can only move in one direction. Segments are called Okazaki Fragments.
A = B + C ---------- --------------------- (________) ( _______________) A = B + C ------------- --------------------- (Substrate) ( Products)
Created by: griffgra
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