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Cell Growth
and division
| Question | Answer |
|---|---|
| The ______ a cell becomes, the more demands the cells places on its ___. | larger; DNA |
| What is less efficient in a larger cell? | moving nutrients and waste materials across the cell membrane |
| Why is a cell's size limited? | volume increases faster than surface area, and homeostasis is disrupted |
| What happens before cell division happens? | the cell replicates all of its DNA |
| Why does cell division work? | cell division solves the problem of increasing size by reducing cell volume; it results in an increase in the ratio of surface area to volume |
| Is cell division mitosis or meiosis? | mitosis |
| What is asexual reproduction? | the production of a genetically identical offspring from a single parent |
| What is sexual reproduction? | involves the fusion of two separate parent cells - zygote; offspring produced inherit some of their genetic information from each parent |
| What is a prokaryote? | unicellular organisms that lack nuclei |
| Where are DNA molecules found? | in the cytoplasm along with most of the other contents of the cell |
| Most prokaryotes contain a ________, circular ___ chromosome that contains all, or nearly all, of the cell's genetic information. | singular; DNA |
| Why do eukaryotic cells contain multiple chromosomes? | eukaryotic cells generally have much more DNA than prokaryotes have |
| What is chromatin? | a substance found in eukaryotic chromosomes that consists of DNA tightly coiled around histones |
| The ______ is filled with a loose tangle of chromatin. | nucleus |
| What is chromatin made up of? | DNA and proteins |
| Together, what does DNA that tightly coils around histones make? | bead-like structures called nucleosomes |
| What nucleosomes pack together to form? | thick fibers, which condense even further during cell division |
| When cell division begins the arrangement of DNA changes how? | it changes from chromatin to chromosomes |
| What 2 identical parts do chromosomes consist of? | chromatids |
| What is the point at which chromatids are joined? | centromere |
| What are the four phases that make up the eukaryotic cell cycle? | G1(cell growth), S(DNA replication), G2(preparation for mitosis), and M(mitosis/cytokinesis) |
| What happens during cell interphase? | the cell interphase is the longest part of the cell cycle; cells double in size; organelles double in #, and DNA copies itself |
| Interphase is divided into what three parts? | G1, S, and G2 |
| What happens during the G1 phase? | cells increase in size and synthesize new proteins and organelles |
| What happens during the S phase? | new DNA are synthesized when the chromosomes are replicated; the cell at the end of the S phase contains twice as much DNA as it did at the beginning |
| What happens during the G2 phase? | many of the organelles and molecules required for cell division are produced |
| What happens during the M phase? | two daughter cells are produced; follows the interphase |
| How many stages does cell division occur in? | two main stages |
| What is the first stage of cell division? | the division of the cell nucleus, mitosis |
| What is the second stage of cell division? | the division of cytoplasm, cytokinesis |
| What is mitosis? | the division of the cell nucleus in which the chromosomes divide into 2 identical sets |
| What happens in the beginning of the prophase? | the genetic material inside the nucleus condenses and the duplicated chromosomes become visible |
| What happens outside the nucleus during prophase? | a spindle starts to form |
| Where can the duplicated strands of the DNA molecule be seen? | attached along their length at an area called the centromere |
| What are the DNA strands in duplicated chromosomes referred to as? | chromatids |
| What is a spindle? | a fanlike system of microtubules that will help to separate the duplicated chromosomes |
| Where do spindle fibers extend from? | the centrosome |
| Where are centrioles located? | in the centrosome |
| What happens as prophase ends? | the chromosomes coil tighter, the nucleolus 'disappears', and the nuclear envelope breaks down |
| What do chromosomes do in the beginning of metaphase? | line up in the middle of the cell, and the centromeres line up across the center of each cell |
| What do spindle fibers do during the metaphase? | connect the centromere of each chromosome to the two poles of the spindle |
| What happens to centromere during anaphase? | it divides, allowing chromatids to separate and move toward centrioles |
| What happens to the chromosomes during anaphase? | they separate and move along the spindle fibers to opposite ends of the cell |
| What happens to centrioles and spindle fibers during telophase? | the disappear |
| What happens to chromatids during telophase? | they unwind and elongate |
| What forms around each mass of chromatin during telophase? | nuclear membrane |
| What happens to chromosomes near the end of telophase? | they begin to spread out into a tangle of chromatin and a nuclear envelope reforms around each cluster of chromosomes |
| What happens to the spindle at the end of telophase? | it begins to break apart and a nucleus becomes visible in each daughter nucleus |
| What does cytokinesis do? | completes the process of cell division - it split one cell into two |
| What is the cell cycle controlled by? | cyclins |
| What are cyclins? | regulatory proteins both inside and outside the cell |
| What cells do not respond to the signals that regulate the growth of most cells? | cancer cells; this causes the cells to divide uncontrollably |
| What happens to cells during the development of an organism? | they differentiate into many types of cells |
| What are stem cells? | the unspecialized cells from which differentiated cells develop |
| What is a totipotent cell? | a cell that is able to do everything, to develop into any type of cell in the body |
| What cells are truly totipotent? | the fertilized egg and the cells produce by the first few cell divisions of embryonic development |
| What is a blastocyst? | a hollow ball of cells with a cluster of cells inside known as the inner cell mass |
| What do the outer cells of blastocysts form? | tissue that attach the embryo to its mother |
| What do the inner cell masses of blastocysts become? | the embryo |
| What is a pluripotent cell? | a cell that can develop into most, but not all, of the body's cell types |
| What is a multipotent cell? | an adult cell that can develop into many types of differentiated cells |
| What is cytokinesis? | the division of cytoplasm |
| In which phase is DNA made? | the "S" phase |
| What is apoptosis? | the death of cells which occurs as a normal and controlled part of a cell's growth |
| What cells does mitosis happen to? | somatic cells |
| What cells does meiosis happen to? | egg and sperm cells |
| Are there cells that do not divide? | yes |
| How do different types of stem cells compare? | the genes within stem cells are the same, but they have different patterns in their gene expression |
| How do zygotes divide and produce more cells? | through the process of mitosis |
| What happens to cells during embryonic development? | cells increase in number and become more specialized |
| How do DNA and genes in different types of cells compare? | the DNA is the same, but different genes are activated |
| Even though all the cells in an individual organism come from a ______ ___, they can specialize into different types of cells. | single cell |
| How do different somatic cells in the same organism compare? | they contain the same genetic and descend from the same cell |
| What types of cells can stem cells produce? | cells that are identical to themselves or more specialized |
| When does the restriction point in the regulation of the cell cycle occur? | at the G1 checkpoint |
| Among the cells in the human body, ______ ____ contain 46 chromosomes whereas the _______ contain 23. | somatic cells; gametes |
| What is the imaginary line along which the chromosomes organize during mitosis? | the metaphase plate |
| What is density-dependent inhibition? | the phenomenon exhibited by most anchorage dependent cells that stop dividing once a critical cell density is reached |
| Because plant cells lack a cleavage furrow, they utilize a ____ _____ to divide into daughter cells. | cell plate |
| A specific kind of mutation causes defective proteins that participate in the formation of the cleavage furrow. Which of the following mitotic phases will be affected? | telophase |
| What is the best explanation for the failure to observe chromosomes through a microscope in human cells? | the cells are in the G0 phase |
| During which phase does DNA synthesis occur in the cell cycle? | S phase |
| What is the primary function of kinetochores? | to connect sister chromatids to fibers attached to the cell's poles |
| Which of the cell cycle phases are part of a dividing pathway? | G1, G2, M and S phase |
| Cells that will divide only if they are attached to an extracellular membrane are demonstrating _________ __________. | anchorage dependence |
| What are some tumor types that have migrated beyond their original location? | metastasis and malignant tumor; not benign tumors |
| Chromatin is a complex of ___ and ________. | DNA and proteins |
| How is the prokaryotic genome different than the eukaryotic genome? | prokaryotic genome is contained in a single DNA molecule |
| When does prometaphase occur? | before metaphase |