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Fluid Movement

Balancing Fluids

QuestionAnswer
Water evaporation from skin is related to BSA so why are little babies at a higher risk for fluid loss than grown people? because their BSA relative to their weight is higher when compared to adults
Insensible fluid loss that cannot be measured
Sensible fluid loss that can be measured
Sources of insensible fluid loss breathing – Tachypnea = more loss, bradypnea = less; skin- humidity affects the amount lost
What is the average adult intake and output? 2, 600mL
What is the average amount of fluid lost through the skin? 600mL
What is the average amount of fluid lost through the lungs? 400mL
What is the average daily amount of fluid lost through the kidneys? 1, 500mL
What is the average daily amount of fluid lost trough the intestines? 100mL
Account for 2600mL of intake. 1,500mL liquid intake, 800mL solid foods, 300mL oxidation
5000mL can be lost if this condition is severe. Diarrhea
1,500mL average daily liquid intake and average daily amount eliminated by the kidneys
100mL fluid lost through the intestines
300mL average amount of water provided to the body by oxidation
800mL average amount of liquid intake from solid food
600mL average daily amount of liquid lost through the skin
400mL average amount of liquid lost through the lungs
40% or about 28 liters amount of a person’s weight made up of intracellular fluid
20% or about 14 liters amount of a person’s weight made up of extracellular fluid
75% amount of extracellular fluid that is interstitial
25% amount of extracellular fluid that is plasma (intravascular)
80% the amount of a newborn’s weight that is water
90% the amount of a premature infant’s body weight that is water
60% amount of body weight that is water in a lean adult male
Increased for the elderly Risk for fluid imbalance
45% water content decreases to 45% after age 60
A liquid with equal solute concentration as another Isotonic
What kind of fluid means no fluid shift if found on either side of a semi-permeable membrane? isotonic
Contains less solute concentration than another Hypotonic
What happens to the fluid in a hypotonic solution if placed on one side of a semi-permeable membrane? Fluid shifts to the more concentrated solution
What type of solution is half normal saline considered? hypotonic – less sodium than blood
What type of solution is normal saline? Isotonic – same sodium as blood
Contains more solute concentration than another Hypertonic
Where does fluid go if a hypertonic solution is placed on one side of a semi-permeable membrane? It is drawn into the hypertonic solution.
What type of solution is dextrose 5% in normal saline? Hypertonic – more solutes than blood
Solutes move from an area of higher concentration to an area of lower concentration diffusion
What kind of solution given by IV could cause fluid to shift from the veins to the cells? hypotonic or half normal saline
What kind of solution given by IV could cause fluid to shift from the cells into the blood stream? hypertonic
ATP muscles solutes from an area of lower concentration to an area of higher concentration Active transport
Active transport ATP is utilized to move solutes from an area of lower concentration to an area of higher concentration
What stops all this Fluid Shifting? balance
Osmosis an area of higher solute concentration soaks up water from an area of lower solute concentration - like a sponge
Movement of fluids through capillaries Capillary filtration
Fluid pushing or blood pushing against the capillaries Hydrostatic pressure
Plasma colloid osmotic pressure The water pulling force of albumin in the intravascular space
Reabsorbtion fluid being pulled back into the capillaries
What happens when the pressure inside the capillary is less than the pressure outside of it? Fluid goes into the capillary
What happens when the pressure inside the capillary is more than the pressure outside of it? Fluid goes out of the capillary
What pressure pushes fluid out of capillaries? hydrostatic pressure
What pressure pulls fluid into capillaries? plasma colloid osmotic pressure
A cluster of capillaries that filters blood in the Bowman ’s capsule Glomerulus
180 Liters the amount of blood filtered by nephrons in a day
125mL the amount of blood filtered by nephrons in a minute
1 to 2 Liters the amount of urine produced from all that filtration of blood, so 178 liters are returned to the body filtered
What amount of urine indicates renal failure? less than 20mL per hour or 500mL per day
Two reasons infants and young children pee more than adults 1) higher rate of metabolism produce more waste 2) less efficient kidneys (baby kidneys cannot concentrate urine until about 3 months and don’t work at full power until about age 2)
Reduces dieresis, increases water retention, comes from the hypothalamus and stored in the posterior pituitary gland ADH
Another name for ADH vasopressin
2 things that stimulate the release of ADH Increased serum osmolality and decreased blood volume
4 Steps of fluid adjustment by ADH 1) hypothalamus notices there’s a problem 2) pituitary spits ADH into the blood stream 3) ADH causes kidneys to retain water 4) blood volume increase/serum osmolality decreases
What happens to urine when ADH is working? It becomes more concentrated
Two things that angiotensin II does peripheral vasoconstriction and stimulate adrenal glands to produce aldosterone
Describe the steps in the rennin-angiotensin-aldosterone system low pressure in the glomerulus causes the juxtaglomerular cells to secrete renin; renin goes to the liver and converts angiotensinogen into angiotensin 1; in the lungs 1 become 2; 2 causes vasoconstriction and release of adolsterone.
How does the renin-angiotensin-aldosterone system turn off? when blood pressure returns to normal the juxtaglomerular cells stop making renin
Two things that activate renin secretion 1) low blood flow to kidneys 2) reduced sodium content in the blood reaching the kidneys
Two things that turn off renin secretion higher blood pressure or more sodium reaches the kidneys
What does aldosterone cause the kidneys to reabsorb? sodium and water
Initiates the active transport of sodium from the distal tubules and the collecting ducts into the bloodstream aldosterone
What happens when aldosterone forces more sodium into the blood stream? the blood volume increases because water follows sodium
Where does ANP come from? The cells of the atria
What causes the release of ANP? Increased pressure in the artia
What does arterial natriuretic peptide do? It counteracts the renin angiotensin aldosterone system by reducing intravascular blood volume and pressure
Name 4 things that ANP does. 1) suppresses serum renin levels 2) decreases release of aldosterone 3) decreases release of ADH 4) causes vasodilation
Two conditions that would cause the amount of ANP released by the atria to increase Chronic renal failure and heart failure
Fluid in the cerebrospinal column, pleural cavity, lymph system, joints and eyes that remains fairly constant transcellular fluid
What is the normal range for serum osmalality? 275 to 295 mOsm/kg
Serum osmolality below 275 Water excess/ solute deficit
Serum osmolality above 295 Water deficit / solute excess
What is the formula for figuring effective serum osmolality? Effective Osmolality = (2 x NA+) + (glucose/18)
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