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WVSOM FA -- 9
WVSOM -- First Aid Classic Labs/Findings Page 3
Question | Answer |
---|---|
Increased α-fetoprotein in amniotic fluid/maternal serum | Anecephaly, spina bifida (neural tube defects) |
increased uric acid levels | Gout, Lesch-Nyhan syndrome, myeloproliferative disorders, loop and thiazide diuretics |
Intranuclear eosinphilic droplet-like bodies | Cowdry type A bodies (HSV or yellow fever) |
Iron-containing nodules in alveolar septum | ferruginous bodies (asbestosis: increased chance of mesothelioma) |
Large lysosomal vesicles in phagocytes, immunocompromised | Chediak-Higashi disease (failure of phagolysosome formation) |
Low serum ceruloplsamin | Wilson's disease (hepatolenticular degneration) |
"lumpy-bumpy" appearance of glomeruli on immunofluorescence | post-streptococcal glomerulonephritis |
lytic ("hole-punched") bone lesions on x-ray | Multiple myeloma |
Mammary gland ("blue-domed") cyst | Fibrocytsic change of the breast |
monoclonal antibody spike | 1. Multiple Myelmoa (M protein) 2. monoclonal gammopathy of undetermined significance (MGUS) 3. Waldenstrom's Macroglobulinemia (M protein) |
Monoclonal globulin protein in blood/urine | Bence Jones proteins Waldenstrom's macroglobulinemia (IgM) |
Mucin-filled cell with peripheral nucleus | signet ring (gastric carcinoma) |
Narrowing of bowel lumen on barium radiograph | "string sign" (Crohn's Disease) |
Needle-shaped, negatively birefringement crystaals | Gout (hyperuricemia) |
Nodular Hyaline deposits in glomeruli | Kimmelsteil-Wilson nodules (diabetic nephropathy) |
"nutmeg" appearance of liver | Crhonic passive congestion of liver due to right heart failure |
"onion-skin" periosteal reaction | Ewing's sarcoma (malignant round-cell tumor) |
Periosteum raided from bone, creating triangular area | Codman's triangle on x-ray (osteosarcoma, Ewing's sarcoma, pyogenic osteomyelitis) |
podocyte fusion on EM | minimal change disease (child with nephrotic syndrome) |
Polished, "ivory-like" appearance of bone at cartilage erosion | Eburnation (osteoarthritis resulting in bony sclerosis) |
protein aggregates in neurons from hyperphosphorylation of protein tau | neurofibrillary tangles (alzheimer's disease and CJD) |
pseudopalisade tumor cell arrangement | glioblastoma multiforme |
RBC casts in urine | acute glomerulonephritis |
rectangular, crystal-like inclusions in leydig cells | Reinke crystals (ledig cell tumor) |