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Lex Angio II Rec Ant
NCLEX Review
| Question | Answer |
|---|---|
| Angiotensin II Receptor Antagonists | Antihypertensives |
| Indications | HTN, CHF for pts who can't tolerate ACE inhibitors |
| Action | Block vasoconstrictor and aldosterone porducing effects of angiotensin II at receptor sites, including vascular smooth muscle and the adrenal glands |
| Therapeutic Effect | Lowering of blood pressure, slowed progression of diabetic nephropathy, decreased risk of stroke |
| Ends in | -sartan |
| Examples | Losartan, valsartan, oprosartan |
| Contraindications | Pregnancy/lactation |
| Use cautiously | CHF, Impaired renal function, black pts, may not work |
| Nursing | Assess BP, angioedema, in CHF intake, outpput, breath sounds |
| Labs | Creatinine, bilirubin, potassium |
| Angioedema | Dyspnea, facial swelling |
| Patient teaching | Change positions slowly, may cause dizziness, |
| Adverse effects | dizziness, fatigue, HA, hypotension, diarrhea, hyperkalemia |