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WVSOM CV PHARM

WVSOM COMLEX CARDIO PHARM

QuestionAnswer
Adenosine MOA: opens K channels and blocks Ca influx in SA/AV nodes, slows AV conduction, increases AV refractory period USE: SVT SE: transient asystole
Amiodarone MOA: Blocks K, Ca and Na channels and B receptors USE: SVT, V tach, V fib SE: Hypo/hyperthyroidism, photosensitivity, BLUE/GRAY SKIN, PULMONARY FIBROSIS
Carvedilol MOA: Blocks B1, B2 and Alpha 1 receptors, vasodilation USE: Heart failure, decrease cardiac remodeling, HTN SE: orthostatic hypotension, dizziness, fatigue, bradycardia
Clonidine MOA: Alpha 2 agonist USE: HTN, opioid withdrawal SE: sedation and dry mouth
Digoxin MOA: Inhibit Na/K ATPase, increase intracellular Ca USE: Heart Failure SE: cardiac arrhythmias, nausea, vomiting, blurred vision, yellow vision
Dofetilide MOA: K channel blocker USE: prvention and treatment of A.fib and A. flutter SE: QT prolongation, torsades de pointes
Esmolol MOA: B-1 blocker USE: Class 2 Antiarrhythmic agent, Sinus Tach, SVT SE: hypotension, bradycardia
Fenoldopam MOA: D-1 agonist, arteriolar vasodilation, increase renal blood flow USE: Hypertensive Emergencies SE: hypotension, decreased serum K level
Hydralazine MOA: Alters intracellular Ca, vasodilation of arterioles, decrease afterload USE: HTN, Heart Failure SE: Edema, refelx tachycardia, MI, lupus syndrome
Mannitol MOA: Osmotic Diuretic USE: Oliguric renal failure, cerebral edema, acute glaucoma SE: Transient volume expansion, pulmonary edema, HF
Methyldopa MOA: Alpha 2 agonist USE: HTN in pregnancy SE: Positive Direct Coombs test, hemolytic anemia
Minoxidil MOA: opens K channels in vascular smooth muscle USE: Severe HTN, Topical tx of Alopecia SE: reflex tachycardia, angina, pericarditis, edema, pulmonary HTN, hypertricosis
Nesiritide MOA: Recombinant human B-type natriuretic peptide, dilates venous/arterial smooth muscle, decrease venous pressure/preload/congestion, dyspnea USE: Heart Failure SE: Hypotension
Nitroglycerin MOA: releases NO causing vasodilation, increase coronary blood flow, decrease O2 demand USE: Stable angina SE: headache, hypotension, syncope, reflex tachycardia
Nitroprusside MOA: vasodilator of both venous and arteriolar smooth muscle USE: HTN crisis, Acute HF SE: Cyanide toxicity, hypotension, headache
Propafenone MOA: Blocks Na channels (Class 1C) in cardiac tissue USE: SVT, life threatening ventricular arrythmias SE: arrythmia, GI disturbances, dizziness
Quinidine MOA: Blocks Na (Class 1A) and K channels in cardiac tissue USE: SVT and Ventricular arrythmias SE: arrhythmia, blurred vision, tinnitus, photophobia, diarrhea
Sotalol MOA: Class 3 K channel blocker USE: SVT, life threatening Ventricular Arrhythmias SE: arrythmias, torsades
Created by: erint