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Pharm 2
Targeted Therapy
| Question | Answer |
|---|---|
| Block communication pathway | Kinase inhibitors |
| Prevent the degrading of proteins | Proteasome inhibitors |
| Assist the immune system | Monoclonal antibodies |
| inhibit formation of new blood vessels | Angiogenesis inhibitors |
| A patient receiving erlotinib asks why it is important to prevent the formation of blood vessels. Which response would the nurse provide? | “Blood vessels allow cancer cells travel to distant sites.” |
| A patient diagnosed with leukemia is to receive imatinib. Before initiating imatinib, the nurse would ensure the patient is positive for which chromosomal abnormality? | Ph+ |
| A patient whose diet consists of fried foods is prescribed sorafenib. Which information on the drug-food interactions would the nurse provide to the patient? | High-fat foods decrease the bioavailability of sorafenib. |
| A patient who has been on sorafenib for advanced renal cancer started taking St. John’s wort for depression. Which effects would the nurse assess as a result of the drug-herbal interaction? | Increased proliferation of cancer cells |
| A patient is prescribed erlotinib and gemcitabine for pancreatic cancer. Which information would the nurse provide regarding the risk for infection? | Risk for infection will increase. |
| A patient is prescribed temsirolimus for advanced renal cell cancer. Before the administration of temsirolimus, which substance would the nurse most likely administer? | Antihistamine |
| A patient is prescribed rituximab for chronic lymphocytic leukemia. Which condition would the nurse teach the patient to seek immediate medical care? | Chest pain |
| A patient receiving targeted antineoplastic drug reports not wanting to eat at mealtimes. Which action would the nurse take first? | Determine the reason for not wanting to eat. |
| Which targeted antineoplastic drugs would most likely interact with St. John’s wort? | -Erlotinib -Sorafenib -Bortezomib -Temsirolimus |
| Bortezomib is prescribed to a patient who is on prednisone, a hepatic inhibitor. Which change to the dose of bortezomib would the nurse expect? | Decreased dose of bortezomib |
Created by:
Lightnning54
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