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Bac, & viral Disease

Microbiology 1 final

QuestionAnswer
Streptococcal Diseases Strep throat Scarlett fever Necrotising Fascitis
Streptococcal disease microbe? Streprococcus Pyrogenes Chains of Gram Pos cocci in lungs/throat ears/ respiratory problems in skin, fleash eating bacteria w/ extra toxin gene, Scarlet fever (breaks capillaries)
Diptheria Disease symptoms Toxin kills epithelial cells of pharnyx, dead cells, mucus, WBC & fibers create pseudo membrane - can be fatal
Diptheria microbe Corynebactrum bipheria (gram Pos)
Pertussis Whooping Cough symptoms 100 day cough
Pertussis Whooping Cough microbe Bordetella Pertussis, Vaccine is DTaP Diptheria, tetenus, acellular Pertusis
Meningococcal meningitis symptoms gets in through res. tract, into blood vessels and cerebrospinal fluid (inflamation of mennenges)
Meningococcal meningitis microbe Neisseria Menngitiois, Gram (-) neg. TREAT: antibiotic and antitoxin (neutralize poison bacteria produce)
Haemophilus meningitis Haemophilus Influenza, type B; not related to the flu, Vaccine in USA 1987, 5% mortality
Tuberculosis microbe Mycobacterum Tuberculosis, (acid fast, rod staining)
Tuberculosis symptoms fever, blood in sputum, chest pain, night sweats, weight loss. Forms tubercles. Consumption. Kills up to a million peeps a year
Tuberculosis treatment open air, Isoniazid, Ritampicin, antibiotics
Primary Atypical pneumonia microbe Mycoplasma pneumoniae, 0.2 micrometers, the smallest pneumonia
Primary Atypical pneumonia description occurs in healthy people, "walking pneumonia", no cell wall in a micoplasma so penicillion won't work
Primary Atypical pneumonia treatment antibiotics to target ribosome Diagosis, cast test (antibodies will clump)s (tetracycline/ erythromycin)
Pneumococcal Pneumonia microbe Streptococcus pneumonia (resident organism that usually doesn't cause disease)
Pneumococcal Pneumonia description fluid in lungs, targets elderly & Secondarily immune compromised individuals, tens of thousands of fatalities in US every year.
Other pneumonia causing bacteria Klebsiella pneumonia & Serratia marcascens: Nosocomial infections (acquired in healthcare setting) health care workers (yikes), lung infections & UTI's
Legionnaires Disease microbe Legionella pneumophila (phila = like) Gram Neg, Diff to grow in lab, grows in standing water & air conditioners
Legionnaires Disease description Mortality rate of 15 to 20%, first outbreak killed lots of vets, Treatment: Erythromycin
Q Fever Description microbe: Coxiella Burnetti, Type: Rickettsiae (very small) causes: contact with animals
Psittacosis Description Pron "sitaki" Chlamidia psittaci, mild infection, get from birds.
Intoxications VS infections Food borne: Intoxication from toxins/poisons Infections from live bacteria
Staphylococcal food poisoning (most common after salmonella) S. Aureus - clusters of spheres (nasal passage, throat, hair, skin; very common; fast incubation (1-6); grows well on meats, dairy, potato salad; Produces exotoxin/ enterotoxin(abdominal symptoms, nonlethal)
Botulims microbe Clostridium Botulism, the most lethal bacteria on earth, Anerobic, spores, powerful nerve toxin, canned food & honey, flacid paralysis
Salmonellosis (all) Salmonella genus, high incidence in US, get from poultry, eggs, mayo, fever, diarrhea, reactive arthritis
Typhoid fever (all) Typhos (cloudy or smoky) Salmonella Typhi,(sewage & foods) FROM: poultry, mayo, etc SYM: bloody stool, fever, delirium. Ulcerate intestines & pass to blood. may get "reactive arthritis" Decimated populations
Typhoid Fever transmission the five F's: fleas, food, feces, fomites (objects) ____ one more??
Typhoid Mary Carriers: 5% shed Salmonella Typhi, but have no symptoms. She was a cook who gave it to 28 people.
Shigllosis (causes 2 diseases: shigellosis & dysentery) shigellosis: small intestine infection (watery diahhrea); Dysentary: Lg intestine (bloody stool w/cramping). dirty water, food, shellfish (veggies washed in dirty water). Severe dehydration possible, treat symptoms only.
Cholera Vibro Cholerae: shellfish, oysters, or fecal contaminated water. Intense "rice water stools", dehydrate (no urine, thick blood, wrinkle skin) TRT: Tetracycline & rehydration
Cholera Epidemics 7 pandemics since 1800's
E coli Gm (-) NEG w/ pili for attachment, gastroenteritis, Complications: HUS (kidney failure, hemeragic colitis), DANGEROUS: E coli 0157:H7, mutates by transduction
Transduction a bacterial gene is transferred to another bacterium by a virus
Peptic Ulcer Disease Heleobactor Pilori, Has urase enzyme: breaks down urea in stomach (neutralizes acid) & breaks down stomach linig, DX: breath test. CONT: person to person TRT: heavy does tetracyclines for months.
Listeriosis Listeria Monocytogenes, contaminated meat, milk & cheese, Affects monocytes (immune syastem), psychrotrophic
Psychrotrophic Grows in refrigerator
microaerophile likes a little O2 = Campylobacteriosis
Campylobacteriosis On of the most common diseases in US, Diarrhea fever, cramps; contaminated poultry; sometimes fatal; COMP: Guilian Barre
Brucellosis Brucella species, Get from animals, raw milk, open wounds; RARE farmers & vets; Undulant fever, TRT: Doxycycline/ Rifampin
Strepococcus Mutans Plaque on teeth, 20 types of bacteria cause biofilms SYM: caries (sugar digest by bac, secrete acid)& gingivitis
Anthrax Bacillus Anthraxis, Toxin producing bac., kills cells, respiratory (often fatal) 7 cutaneous
Tetanus Clostridium tetani, secretes toxin that blocks muscle relaxation, anerobic, from soil, vaccine
DTaP Diptheria, tetanus, pertussis
Gas Gangrene Clostridium perfringens, (soil) bac. forms toxins, "gangrene" = blood flow stopped. wet gangrene ferments proteins & carbs to gas.
Bacteria that produce toxins: Gangrene (clostridium perfringes), tetanus (clostridium tetani), Clostridium botulinum: botulinum, Anthrax (bacillus anthraxis),Corynebacterium diphtheriae: diptheria, Bordetella pertussis: pertussis toxin Vibrio cholerae: cholera,
Bubonic Plague Versina Pestis (from pest-flea), Lungs> contagious & fatal, blood (septicemic) fatal, Boboes> purple lesions at lymph
Rocky Mountain spotted fever Rickettsia Rickettsii (Ricketty tick), fever & rash, (Dox & Amox)
Lyme Disease Borrelia burgdorferi (BB like Bambi), spirochete, (Dox & Amox), can result in chronic arthritis
Typhus Fever (not Typhoid) Rickettsia Prowazekii, lice,
Difference between Typhus fever and typhoid fever Typhus = lice borne, INFECTION (high fever) Rickettsia prowazekii. Typhoid Fever = Food poisoning, (bloody stool) INTOXICATION, Salmonella typhi, 5 f's food, fleas, feces, fomites
The 5 F's Food, feces, fingers, fomites, fleas
Leprosy mycobacterium leprae (like TB, eats tissue), 3 - YEAR incubation, disfiguring (lepromas), nerve damage
Zap it with Dap Dapsone > leprosy, malaria, PCP (MDT, multi)
ABC infections Abcess (pus filled lesion) Boil (infected hair follicle) Carbuncle (a series of connected boils)
Staphylcoccal infections Staphyloccus aurus, ABC infection, the most dangerous staph, can penetrate to blood, MRSA/ VRSA Methicillin/ Vancomycin
Toxic Shock Syndrome strain of SA, Makes Toxin, lacerates tissues, bloodstream, lack of O2, (tattoos, tampons)
Trachoma Chlamydial Trachomas, #1 cause of preventable blindness (omas - tumors)
Streptococcal Diseases Scarlett fever, Narcotizing fasciitis
Yaws (raspberry) spirochete, like syphilis organism
UTI E. Coli & others, pili help attach
Syphilis Treponema Pallidum = spitochete, 3 stages: Chancre, rash, rumma (lesion/ CNS degrneration, sex & placenta
Gonorrhea Neisseria Gonorrhoeae,n gm neg dipplococcus,
Chlamydial urethritis Chlamydia Trachomatis, (urinary TRACH)#1 infectious disease (STD) (Matis, inflammations) BOTH END IN TIS
Influenza Recombant RNA virus, 9-15 HN spikes (attachment/ release), Antigenic shift - major changes to flu genome RESPIRATORY
Parainfluenza kids under 6, misdiagnosed as cold
Adenovirus common cold (20 viruses)
Rhinovirus/ Corona virus inflammation upper respiratory tract. 60% on hands. Corona, crown spike proteins
SARS variant corona virus, 2003, severe pneumonia
RSD = resp syncytial disease babies, viral pneumonia, syncytia = giant cell fusions
synagist Immune Globulin
Herpes Simplex Herpes = "to creep" infects nerves under skin, 90% exposed, type 1 mouth, type 2
Provirus Goes latent, hides, recurrent attacks under stress
Base Analog Fake nucleotide (fake G) Acyclovir: anti viral
Kaposi's sarcoma provirus gets in genes & mutates DNA, (MUTAGEN)
Chicken pox/ shingles VZV - Herpes varicella/ Herpes zoster (girdle) not true pox.
Asprin Reyes Syndrome
Smallpox Variola virus 30% fatal, spread by resp droplets, huge fluid-filled vesicles, totally ERADICATED 1979, bio terrorism threat
Monkeypox came to America in prairie dogs and Gambian rats.
Papilloma virus HPV: herpes, provirus, warts & cervical cancer
measles red w/white centers, koplik spots in mouth, cause encephalitis
Mumps virus blocks parotid (saliva) glands, can affect testes (orchitis)
Rubella German measeles, rash is flat, vertical transmission
vertical transmission mom to fetus
MMR attenuated live vaccine
fifth disease 5 rash diseases, slapped cheek
Yellow Fever virus, mosquito vector, fever jaundice, internal bleeding (30,000 deaths annually)
Jaundice liver infection - improper breakdown of RBC or overflow of bile into blood
ARBOvirus Arthropod Borne
Dengue Fever RNA virus, 4 serotypes,
Infectious mononucleosis EBV = Epstien Barr Virus, Herpes virus, children & young adults, spleen rupture burkitt's lymphoma (africa),
Hep A (acute) A & E food & water borne, Acute lasts 2 weeks to 6 months, nausea, vomiting, jaundice, liver enlargement (all Hep have some)
Hep B (body fluids) Body fluids, incubate 4-6 months, complication: liver cancer, Treat: immuunoglobulin/ interferon Can be with Hep D
Hep C (chronic) STD & needles, slow but deadly, cirrhosis & lover failure, #1 reason for liver transplants
Viral Gastroenteritis Rotavirus (worse, Norvirus (cruise ships) inflammation of GI, dehydration kills 600,000 kids per year
Lassa Fever Rats (eating or preparing), potentially deadly hemorrhagic fever
Ebola virus Filoviridae family (needle & thread) melts your organs, 50 - 90% mortallity, similar Marurgh virus,
HIV/ AIDS + RNA virus, reverse transcriptase to make DNA copy & hide in DNA, destroys immune system, when T helper cells beloww 200 = AIDS
Rabies Rhabdoviridae family = bullet shaped, single strand RNA, spinal cord & brain degenerate, hydrophobia, death from respiratory paralysis, Dumb and violent rabies.
Rabies incubation 2 months to a year, so can get the sh
Polio a pico virus, one of the smallest, contaminated food & water, paralysis, may be the next one eradicated
CMV Cytomegalovirus Eyes & brain, produce serious birth defects, vertical transmission-microcephaly
West Nile arbovirus, encephilitis
Varient CJD Prion disease, infectious proteins that cause fatal brain diseases
Amoebiasis Entamoeba Histolytica-tissue breaker, 2nd only to malaria for death. water, cysts
PAM Primary Amoebic Meningoenchelitis killer amoeba, naegleria fowleri. 95% death, waterborne through nose
Giardiasis most common protozoal disease in US, sewage/water, enterotest capsule on a string
African sleeping sickness/ Chagas disease Trypanosomiasis, 2 different diseases, ASS = tsetse fly (brain damage)/ Chagas = kissing bug(heart damage) Killed Darwin.
Leishmaniasis Rose of Jerico (congrgate, soldier in the desert get it, Baghdad boil (can be lethal)
Trichomoniasis STD, Trichomonis Vaginalis, flagellate,
Balantidiasis B coli, ciliate (hair-like/only path. one), cyst/ water (fecal oral)/ trophozoites
Toxoplasmosis Apicomplexan from cats, rats>birds> cats Toxoplasmosa gondi (protozoa)
Vertical transmission TORCH Toxoplasmosis, Other (HIV), Rubella, Cytomegaiaovirus, Herpes Simplex
Cryptosporidiosis Protazoa, America> swimming pool (survives chlorination), low dose (only 30 organisms) lead to infection. Intense diarrhea
Apicomplexan (Plasmodium) disease Malaria, every 3-4 days comunicate & explode cells > fever > chills during recovery
Know the killers HIV, TB, Malaria, Staff, Antanoeba, hanta virus
Cryptococcosis Mycosis - fungal, airborne/ bird droppings/ 25% of fungal deaths, lungs/ body cavities - treatable, but dangerous (Amphoterican)
Candidiasis mycosis (fungal), Candida Albicans, vulovaginitis, oral (cottage cheese), intestinal
Dermotophytosis Tinea infections, tinea capitus, tinea pedus, tinea curis
Histoplasmosis Histoplasma capsulatum (encapsilated spore), lungs & spores, birds & bat droppings,
Blastomycosis Blastomyces dermatitidis, lungs to skin or bones, very common in SE US. Untreated can be fatal
Pneumo-cystic Pneumonia (PCP) Fungal pneumonia, kills AIDS patients, resembles both fungus & animal (protozoa)
Aspergillosis Aspergillus flavus: produces aflatoxin: accute hepititis/ heptic carcinoma (corn, peanuts, wet carpet)
Ergot poisioning Salem witch, fungus on cereal plants or rye, cause hallucinations, convulsions, death
Created by: onesmartgirl
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