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chpt25antibacterial
meds, actions, keyterms
| Question | Answer |
|---|---|
| anarobic | able to live w/out oxygen |
| anaphylactoid reaction | unusual or exaggerated allergic reaction |
| anaphylactic shock | severe form of hypersensitivity reaction |
| antibacterial | against active bacteria |
| bactericidal | agent or drug that destroys bacteria |
| bacterial resistance | ability if bacteria to produce substances that inactivate or destroy the impact of a drug |
| bowel prep | use of drugs preoperatively to reduce # of bacteria normally present in intestine |
| cross-allergenicity | allergy to drugs in the same or related group ie cillins |
| leprosy | chronic communicable disease spread by prolonged intimate contact with infected person |
| mycobacterium leprae | bacteria that causes leprosy |
| myobacterium tuberculosis | bacteria causes tuberculosis |
| nonpathogenic | not disease causing |
| penicillanse | enzyme that inactivates penicillin |
| pseudomenbranous colitis | common bacterial superinfection |
| stevens-johnson syndrome | serious allergic reaction to a drug which initally exhibits reactions easily confused with less severe disorders |
| tuberculosis | disease caused by myobacterium tuberculosis |
| bacterial resistance | ability to produce substances that inactivate or destroy penicillin (penicillinase) |
| cillins spectrum | natural penicillin G narrowest spectrum tx. syphilis, gonorrhea |
| Penicillinase-resistant (Nafcillin) | 2 of 4 in spectrum |
| Aminopenicillins (Ampicillin) | 3 0f 4 in spectrum |
| Extended spectrum (TICARrcillin) | broadest spectrum in penicillin |
| Sulfadiazine | UTI,acute otis media, --Stevens-Johnsons syndrome |
| sulfamithizole (Thiosulfil Forte) | UTI |
| sulfamethoxazole(Gantanol) | UTI otitis media, ---stevens-Johnsons Syndrome |
| sulfasalazine (Azulfidine) | RA, ulcerative colitis (urine and skin turns yellow) |
| sulfisoxazole generic | ulcerative colitis RA yellow skin, urine |
| TMP/SMP-trimethoprim/sulfamethoxazole (Bactrim/Septra) | UTI otitis media, E-coli --stevens-Johnsons syndrome |
| nafelnide (Sulfamylon) | 2nd & 3rd degree burns topical AR=pain burning rash facial edema |
| silver sulf-adiazine (Silvadene) | 2-3rd degree burns topical cream AR=Leukopenia, skin necrosis, burning |
| Major adverse reactions Sulonamides | Stevens-Johnson Syndrome, hematologic changes ↓ WBCs, ↓ platelets, anemia |
| Cephalosporins Major adverse reactions DO NOT USE IF ALLERGIC TO PENICILLINS | Nephrotoxicity ↓urine, elderly √ creatinine diarrhea = superinfection, Stevens-Johnsons Syndrome |
| cefadoxil (Duricef) | used w/susceptible bacteria |
| cefazolin sodium (Ancef) | pre-op, susceptible bacteria |
| cephalexin (Keflex) | susceptible bacteria |
| cefaclor (Ceclor) | CROSS SENSIVITY TO PENINICILLINS tx susceptible bacteria |
| Two types major sensivity reactions | |
| Sulfonamides | bacteriostatic, for UTI, avrx hematologic changes, do not use in children under 2 |
| Macrolides | respiratory infect. zithromax, biaxin, erythromycin--end in ycin |
| Fluconazole in elderly | contra renal impairment , creatinine clearance |
Created by:
mttammy
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