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AZT
NCLEX Review
| Question | Answer |
|---|---|
| AZT | Nucleoside reverse transcriptase inhibitors |
| Action | Inhibits viral RNA synthesis by inhibiting enzyme DNA polymerase (reverse transcriptase) |
| Action | Prevents viral replication |
| Therapeutic Effects | Virustatic action against selected retroviruses |
| Adverse Effects | Seizures, HA, weakness, abdominal pain, diarrhea, nausea, anemia, granulocytopenia |
| Nursing implications | Monitor viral load and CD4 counts, CBC, |
| Pt Implications | May cause dizziness, or fainting, notify provider if sore throat or other sings of infection occur, avoid crowds or people with known infections, use soft tooth brush |
| AZT | Retrovir, azidothymidine |