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Pharm 2

Chemotherapeutic Therapy

QuestionAnswer
Antimetabolites Fluorouracil
Plant alkaloids Vincristine
Antitumor antibiotics Doxorubicin
Alkylating drugs Cyclophosphamide
In which phase of the cell cycle do most antimetabolites affect cells? S phase
A patient with multiple myeloma received cyclophosphamide at 0900. Which time would the nurse expect the drug to peak? 1100
Which statements describe the benefits of treating cancer cells with a combination of different classes of chemotherapeutic drugs? -Therapeutic effect in all phases of cancer cells is increased. -Development of drug resistance is decreased. -Destruction of cancer cells is increased
A patient receiving vincristine asks why it must be given intravenously. Which response would the nurse provide to the patient? “Oral administration has a low absorption rate.”
Which statement made by the patient indicates a need for further teaching regarding doxorubicin, an antitumor antibiotic? “I do not have to worry about infection because the drug is an antibiotic.”
A patient is prescribed vincristine for Hodgkin’s lymphoma. On further questioning, the nurse discovers the patient has plant allergies, specifically to periwinkle. Which action would the nurse take? Notify the health care provider.
A nurse is disposing of urine from a patient who is receiving chemotherapeutic drugs. Which action would the nurse take to decrease the risk for occupational exposure? Apply a face shield.
Oral cyclophosphamide 700 mg is prescribed to a patient weighing 125 pounds. Which action would the nurse take first? Hold the drug.
A patient diagnosed with metastatic pancreatic cancer is prescribed fluorouracil as part of a combination regimen with oxaliplatin, leucovorin, and irinotecan. Which treatment cycle would the nurse expect fluorouracil to be repeated? Every 2 weeks
The nurse preparing to administer chemotherapeutic drugs notes the patient has had a significant drop in neutrophils. The nurse would anticipate administering which product into the patient’s plan of care? Colony-stimulating factors (CSFs)
A patient receiving chemotherapeutic drugs complains of mouth lesions and inability to eat or swallow. The nurse notes the patient has opioid analgesic, topical anesthetic, antiemetic, and sedative prescribed. --
Which drug would the nurse most likely provide? Topical anesthetic
A nurse provides teaching to a male patient receiving chemotherapeutic drugs. Which statements made by the patient indicate an understanding of potential side effects of chemotherapeutic drugs? -“I will use a soft toothbrush to brush my teeth.” -“I may need to take stool softeners to avoid constipation.” -“I will bank some of my sperm so I still have the option of having children in the future.”
Created by: Lightnning54
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