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Pharm 2
Chemotherapeutic Therapy
Question | Answer |
---|---|
Antimetabolites | Fluorouracil |
Plant alkaloids | Vincristine |
Antitumor antibiotics | Doxorubicin |
Alkylating drugs | Cyclophosphamide |
In which phase of the cell cycle do most antimetabolites affect cells? | S phase |
A patient with multiple myeloma received cyclophosphamide at 0900. Which time would the nurse expect the drug to peak? | 1100 |
Which statements describe the benefits of treating cancer cells with a combination of different classes of chemotherapeutic drugs? | -Therapeutic effect in all phases of cancer cells is increased. -Development of drug resistance is decreased. -Destruction of cancer cells is increased |
A patient receiving vincristine asks why it must be given intravenously. Which response would the nurse provide to the patient? | “Oral administration has a low absorption rate.” |
Which statement made by the patient indicates a need for further teaching regarding doxorubicin, an antitumor antibiotic? | “I do not have to worry about infection because the drug is an antibiotic.” |
A patient is prescribed vincristine for Hodgkin’s lymphoma. On further questioning, the nurse discovers the patient has plant allergies, specifically to periwinkle. Which action would the nurse take? | Notify the health care provider. |
A nurse is disposing of urine from a patient who is receiving chemotherapeutic drugs. Which action would the nurse take to decrease the risk for occupational exposure? | Apply a face shield. |
Oral cyclophosphamide 700 mg is prescribed to a patient weighing 125 pounds. Which action would the nurse take first? | Hold the drug. |
A patient diagnosed with metastatic pancreatic cancer is prescribed fluorouracil as part of a combination regimen with oxaliplatin, leucovorin, and irinotecan. Which treatment cycle would the nurse expect fluorouracil to be repeated? | Every 2 weeks |
The nurse preparing to administer chemotherapeutic drugs notes the patient has had a significant drop in neutrophils. The nurse would anticipate administering which product into the patient’s plan of care? | Colony-stimulating factors (CSFs) |
A patient receiving chemotherapeutic drugs complains of mouth lesions and inability to eat or swallow. The nurse notes the patient has opioid analgesic, topical anesthetic, antiemetic, and sedative prescribed. | -- |
Which drug would the nurse most likely provide? | Topical anesthetic |
A nurse provides teaching to a male patient receiving chemotherapeutic drugs. Which statements made by the patient indicate an understanding of potential side effects of chemotherapeutic drugs? | -“I will use a soft toothbrush to brush my teeth.” -“I may need to take stool softeners to avoid constipation.” -“I will bank some of my sperm so I still have the option of having children in the future.” |