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Protease

NCLEX Review

QuestionAnswer
Protease inhibitors Lopinavir/ritonavir
Action Inhibit HIV viral protease
Therapeutic effects Increased CD4 counts and decreased viral load with subsequent slowed progression of HIV infection and sequelae
Adverse Reactions Headache, insomnia, weakness, diarrhea, abdominal pain, nausea, pancreatitis, taste aversion, vomiting, rash
Nursing Assess for signs of pancreatitis, vomiting, abdominal pain, increased serum lipase or amylase
Labs Viral load, CD4 counts, triglyceride, cholesterol levels, liver function tests,
Hyperglycemia May cause , notify provider with increased thirst, hunger, unexplained weight loss, or increased urination
Redistribution and accumulation of fat central obestity, dorsocervical fat enlargement, peripheral wasting, breast enlargement, cushingoid apprerance
Created by: schizonurse
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