click below
click below
Normal Size Small Size show me how
Rifampin
NCLEX
Question | Answer |
---|---|
Rifampin | Antituberculars |
Action | Inhibits RNA synthesis by blocking RNA transcription in susceptible organisms |
Therapeutic effect | Bactericidal action against susceptible organism |
Spectrum | Broad spectrum, notable for activity against myobacterium, staphyloccucus, H influenza, Neisseria menigitidis |
Adverse Reactions | red discolaration of body fluids, abdominal pain, diarrhea, heartburn, nausea, vomiting |
Nursing | Assess lung sounds, character |
Labs | CBC, hepatic function, |
PO | Give on empty stomach with 240 ml water, |
Signs and symptoms of hepatitis | yellow eyes, skin, nausea, vomiting, weakness, thrombocytopenia |
Oral contraceptives | Rifampin decreases effectiveness, need non hormonal method |