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Rifampin

NCLEX

QuestionAnswer
Rifampin Antituberculars
Action Inhibits RNA synthesis by blocking RNA transcription in susceptible organisms
Therapeutic effect Bactericidal action against susceptible organism
Spectrum Broad spectrum, notable for activity against myobacterium, staphyloccucus, H influenza, Neisseria menigitidis
Adverse Reactions red discolaration of body fluids, abdominal pain, diarrhea, heartburn, nausea, vomiting
Nursing Assess lung sounds, character
Labs CBC, hepatic function,
PO Give on empty stomach with 240 ml water,
Signs and symptoms of hepatitis yellow eyes, skin, nausea, vomiting, weakness, thrombocytopenia
Oral contraceptives Rifampin decreases effectiveness, need non hormonal method
Created by: schizonurse
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