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Calcium Channel Blkr
NCLEX Review
| Question | Answer |
|---|---|
| Calcium Channel Blockers | HTN, Angina, supraventricular tachyarrhythmias, atrial flutter, fibrillation |
| Action | Inhibits transport of calcium into myocardial and vascular smooth cell, resulting in inhibition of excitation-contraction coupling and subsequent contraction |
| Therapeutic effect | Systmeic vasodilation resulting in decreased blood pressure, suppression of angina |
| Contraindications | 2nd or 3rd degree heart block, blood pressure less than 90, recent MI, pulmonary congestion, concurrent use of rifampin |
| Adverse reactions | periperal edema, gingival hyperplasia |
| Grapefruit juice | increases serum levels and effect |
| Nursing | Assess for signs of CHF |
| Labs | Potassium, hypokalemia increases risk of arrhythmias and should be corrected, may cause an increase in hepatic enzymes |
| end in | ipine |
| Examples | amlodipine, nifedipine, isradipine |
| Other names | verapamil, diltiazem |