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AH III - chapter 53

QuestionAnswer
Liver functions - removes toxic byproducts of meds - metabolizes nutrients to produce energy - removes bacteria from the blood - produces substances that regulate blood clotting - stores vitamins, minerals, & sugar - produces protein - produces bile
3 reasons why there’s bleeding 1) reduced bile (vitamin k) 2) thrombocytopenia 3) clotting factors
Albumin Protein produced by the liver; keeps fluid/plasma in the blood vessels to give us a BP; when it is not being produced -> fluid seeps into the tissue -> edema & ascites (drops BP)
Ascites Huge belly of fluid; can be caused by either portal hypertension or lack of albumin
Paracentesis Solution for ascites; pulling fluid out of belly -> drops BP even more -> give albumin before & maybe after procedure to pull fluid back into vascular space to raise BP
Bile Compound needed to digest fat & to absorb vitamins A, D, E, & K
Portal vein Blood from abdominal organs goes to the liver first vs. the heart (to filter out filth - mcdonald’s scenario)
Liver Sterilization factor for the abdominal organs
Cirrhosis Extensive scarring of the liver, usually caused by a chronic reaction to inflammation & necrosis; scarring -> nodules -> block bile ducts & blood vessels
Causes of cirrhosis Chronic alcoholism, hepatitis, nonalcoholic steatohepatitis (NASH), drugs & toxins, bile duct disease, & genetic diseases
Compensated cirrhosis The liver has significant scarring, but performs essential functions without significant symptoms
Decompensated cirrhosis Liver failure
Portal hypertension Increase in pressure within the portal vein from increased resistance or obstruction of the flow of blood; blood backs up into the spleen -> splenomegaly (spleen enlargement)
Spleen Immune organ & holds a unit of blood & platelets (thrombocytes); on left-side
Esophageal varices Like hemorrhoids (outpouching due to pressure); can bleed (life-threatening)
Third spacing Edema where it’s not expected
Splenomegaly Spleen enlargement from the backup of blood; destroys platelets, causing thrombocytopenia & increased risk of bleeding -> may be the first clinical sign of liver dysfunction
What can cause the varices to pop? Coughing, vomiting, pooping, straining…(Give stool softener)
Jaundice Develops when the liver cells cannot effectively excrete bilirubin; caused from either disease or obstruction (hepatocellular or intrahepatic obstructive); itching is common (*teaching about scratching because of bleeding)
Hepatic encephalopathy Brain fog from liver probs; why? toxins aren’t being taken out & ammonia accumulation because the liver isn’t able to excrete by conversion; causes: high protein diet, infection, hypovolemia & hypokalemia, constipation, GI bleed & drugs
Ammonia Liver breaks down protein into this -> urea -> we pee this out
Lactulose Laxative; used to pull ammonia out
Hepatorenal Syndrome End stage liver -> end stage kidney -> usually endgame; s/s: oliguria & elevated BUN & creatinine
Spontaneous bacterial peritonitis (SBP) Bacteria from bowel wall seeps into the fluid from the ascites; the diagnosis is made from a sample of this ascitic fluid
Hepatitis A Fecal-oral (ex: everyone ate a restaurant & now has it)
Hepatitis B, C, D, & E Blood
Hepatitis The widespread inflammation & infection of liver cells; s/s: abdominal pain, yellowish sclera (icterus), arthralgia, myalgia, diarrhea/constipation, clay-colored stools, dark yellow - brownish urine, jaundice, fatigue, anorexia, nausea, and itching
Hepatitis patient teaching Diet: high is carbohydrates & calories, frequent meals are more preferable than 3 meals a day, & high-calorie snacks may be needed; fatigue: adequate resting periods; avoid crowds & people who are infected
Preventing Hepatitis Hand-washing, avoiding contaminated food or water, receiving immunoglobulin within 14 days if exposed to the virus, avoiding large crowds, & vaccination (A & B)
Created by: tatianalopez03
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