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EXAM 1
Intro to Human Disease
| Question | Answer |
|---|---|
| acute inflammation | sudden, short term |
| vascular response | Change in blood vessels, right after injury. |
| cellular response | Movement of white blood cells to injury site |
| granular | white blood cells |
| nongranular | present in chronic inflammation, development of scar tissue |
| stages of inflammation | Margination, Emigration, Chemotaxis, Phagocytosis |
| margination | fluid leaves cells, cells go to the MARGINS (edges) of blood vessels |
| emigration | go through vessel into tissue |
| chemotaxis | chemicals that transport blood cells into tissues |
| phagocytosis | engulfing and destroying bacteria |
| opsonization | prepares debris to be engulfed |
| engulfment | surrounds debris |
| intracellular killing (destruction) | debris goes into white blood cell, where it destroys bacteria |
| cytokines | mediators of inflammation |
| nonspecific | you will have an accumulation of monocytes and lymphocytes and will have formation of scar tissue. |
| Granulomatous | formations of leisons, splinters |
| tissue repair | inflammatory phase, proliferation phase, maturational phase |
| inflammatory phase | starts at time of injury, promotes inflammation |
| proliferation phase | 2-3 days after injury, start producing new cells to repair the tissue |
| maturational phase | 3 weeks after injury, see remodeling of tissue |
| cells | labile, stabile, permanent |
| labile | continue to divide (mitosis) |
| stabile | only do cell division when stimulated (when there's an injury) |
| permanent | lost ability to undergo cell division (muscle cells) |
| necrosis | tissue death that is still on the body |
| Coagulation | grayish color firm mass, discoloration |
| caseous | milk, you have an abscess with a cheesy like scent. Kind of looks like cottage cheese |
| exodites | fluids that go to injury site to help heal. |
| exogenous | outside of body, cell injury |
| endogenous | inside of body, cell injury |
| gangrene types | dry, moist, gas |
| dry gangrene | the skin looks dry and is dry to the touch, gets wrinkly and shrunken. Color changes, it is dark brown/black. Progresses very slowly. Interruption of artery blood flow. |
| moist gangrene | skin feels moist to the touch, cold, looks swollen, skin looks stretched from the swelling, discoloration of tissue, due to bacterial infection |
| gas gangrene | clostridium (bacteria, doesn’t need oxygen to survive), deep puncture wombs, since no oxygen clostridium will survive when it is a deep puncture womb. Can produce gas bubbles (H₂S). Could go away if treated right away. |
Created by:
Kileye
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