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Lecture 27

Creatinine Phosphate

Is the high energy molecule phosphocreatine generated in times of high or low ATP? High ATP- it stores the extra ATP
What enzymes catalyzes the reaction creatine + ATP --> Phosphocreatine? CPK- Creatine phosphokinase
How is creatinine formed? phosphocreatine naturally breaks down into creatinine which is released in the blood
Why are high levels of creatinine a sign that your kidney isn't working properly? The kidneys normally clear the creatinine from your blood
Why does finding CPK in the blood indicate you have a heart problem? Normally CPK is found within the heart cells. If there is sufficient damage, your heart cells will lyse and release the CPK into the blood
Created by: bettyboucher