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Bio Exam 1

TermDefinition
Bacteria contain prokaryotes - single celled organisms that lack a nucleus, Unicellular, Often associate and can combine however are not considered tissue, Biofilm often comes as a result of many bacteria combining together
Eukarya Some eukaryotes are single celled, others are multicellular (like humans) - Contains everything from single celled Fungi (yeast) to Animals and Humans
Archaea contain prokaryotes - single celled organisms that lack a nucleus, Found in extreme environments, Originally associated with bacteria however they have the ability to survive in many extreme environments
Atoms 92 naturally occurring, 13 used in life
Molecules formed of atoms
Cells Cells are the smallest structural and functional unit of an organism For Bacteria, Archaea, and other unicellular organisms, THE CELL IS THE ORGANISM
Tissues made of many cells working in unison
Organs made of several tissue types
Organ Systems containing groups of organs that work together
Organism being a collection of organ systems
Species are groups of interbreeding organisms
Population the members of a species in a particular area
Ecosystem community of populations (*biotic*) interacting in physical environments (*abiotic*)
Community interacting species
Biosphere all of earths ecosystems
Energy the capacity to do work
Metabolism sum of all the chemical reactions that occur within a cell or organism
Photosynthesis used by plants, algae and some bacteria
What is the ultimate source if energy? THE SUN
Homeostasis a constant internal environment
external stimuli changes outside the body
internal stimuli adjustments to blood pressure in response to values outside of normal
asexual reproduction 1 individual dividing into 2 (cloning) seen with prokaryotic cells
sexual reproduction 2 individuals (one with eggs and one with sperm) off spring gets 23 chromosomes from each parent
Growth increase in size and in the number of cells
development all changes that occur from fertilization until death
DNA (deoxyribonucleic acid) The genetic information of life - contains hereditary information that directs the structure and function of all cells - contains genes: short segments that specify traits
Mutations variations in gene due to uncorrected errors in DNA when it is copied
Evolution how a populations changes over time
Natural Selection a process by which evolution occurs When a new variation occurs that allows organisms to capture more resources, those individuals have more offspring
Adaptation over time, population has more individuals with this advantageous variation
Matter Anything that has mass and takes up space.
Elements basic building blocks of matter; cannot be broken down by chemical means. Over 90% of the human body is made up of only four elements: carbon (C), nitrogen (N), oxygen (O) and hydrogen (H)
C Carbon
H Hydrogen
O Oxygen
P Phosphorus
K Potassium
I Iodine
N Nitrogen
S Sulfur
Ca Calcium
Fe iron
Mg Magnesium
Na Sodium
Cl Chlorine
3 subatomic particles protons, neutrons, electrons
Max electrons in the closest shell? 2
Max electrons in outer shells? 8
What is the outer most atomic shell? Valence shell
Atomic Number The number of protons
Mass Number sum of the number of protons and neutrons Protons and neutrons each have a mass equal to one atomic mass unit (AMU) Electrons have negligible mass
Radioisotopes unstable isotopes; they emit energy called radiation Radiation can damage cells and cause cancer Useful for imaging the body, killing bacteria in food, sterilizing equipment and killing cancer cells
Isotopes atoms of the same element (with the same atomic number) but a different number of neutrons They differ in their mass number
Compounds molecules made of atoms of different elements bonded together
ionic bond When an atom takes an electron and another atom gives an electron
covalent bond When atoms share electrons
double covalent bond sharing 2 pairs of electrons
triple covalent bond sharing 3 pairs of electrons
Nonpolar covalent bond When atoms share an electron equally, most commonly with itself
polar covalent bond when atoms share an electron unequally
Properties of water 1. Water is liquid at room temp 2. High heat capacity 3. High heat of vaporization 4. Water is a solvent 5. Water molecules are cohesive and adhesive 6. Frozen water is less dense than liquid water
Calorie amount of heat required to raise one gram of water one degree of Celsius
Solvent dissolves many substances
Solution Water with dissolved solutes
Hydrophilic water loving
Hydrophobic Water fearing
preclinical trials Laboratory studies Duration: several years Provides information on dosing and toxicity levels
Phase 1 trials Safety Duration: several months Evaluate safety Gather information about how a drug interacts with the body
Phase 2 trials Safety and dosing Durations: several months Further evaluate safety Monitor side effects Check which dose works best Check effectiveness
Phase 3 trials Safety and efficacy Duration: several years Confirm effectiveness monitor safety
What is between phase 3 and phase 4 clinical trials? FDA approval
Phase 4 trials Post marketing safety and efficacy Gather information on the drug's effect on various populations and any side effects associated with long-term use
Control Group In an experiment, the group that is not exposed to the treatment; contrasts with the experimental group and serves as a comparison for evaluating the effect of the treatment.
Test Group receives the drug/treatment
Randomized subjects randomly assigned to a group either control or treatment
Single-Blind Study the subjects don't know which group they're in; the researchers do know
Double-Blind study neither doctor nor patients know which group they are in
Informed consent subjects know exactly their role in the study including all risks and benefits; they can withdraw at any time
What is the measure of the acidity or alkalinity of a solution? The pH Scale
What does the pH scale measure? The concentration of hydrogen ions
What is factor of change between each pH number 10x
Substances that dissociate in water, releasing hydrogen ions Acids
Substances that take up hydrogen ions or release hydroxide ions Bases
An example of a strong acid? Hydrochloric Acid (HCl)
An example of a strong base? Sodium Hydroxide (NaOH)
What is a normal pH value for the human stomach? x<3.5
What is a solution that resists changes in pH when acids or bases are added? A buffer
What are two examples of buffers in blood? Carbonic acid and bicarbonate ions
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Created by: h-charles
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