click below
click below
Normal Size Small Size show me how
stem cell & diff
| Question | Answer |
|---|---|
| Specialised cell - type | has modified structures to allow it to carry out a particula function Neuron, RBC, muscle cell Highly specialised cells are unable to divide |
| stem cell - type | unspecialised cell that undergoes cell division and has the ability to produce different types of body cells |
| Proliferation - process | process which cells replicate themselves over & over ( mitosis) |
| Differentiation - process | process by which unspecialized cells develop the characteristics & the functions of a particular cell They become specialized |
| why | result 1 stem cell & 4 new specialised cells Self renewal required to maintain a pool of stem cells. special cells cant reproduce specialised cells function body but die & cant replace themselves |
| How differentiate | Differentiation is triggered by chemical signals in the microenvironment around a cell. These chemicals activate certain genes & cause gene expression of particular genes in each cell |
| stem cell classify | Potency (potential of a stem cell) how many different types of cells the stem can differentiate into Source: where stem cells originate |
| Totipotent | can become ANY cell of the body and the embryonic membranes that surround support & nourish it Cells of the embryo within the first couple of mitotic divisions after fertilization |
| Pluripotent | have ability to form any cell of the body but NOT the embryonic membranes Inner cell mass |
| Multipotent | have ability to form some cells of the body Develop into more than 1 type but not all types Blood stem cell in boe marrow can give rise to RBC WBC & platelets only Found in both embbyros & adults |
| Embryonic | derived from embryos - then inner cell mass of the blastocyst Pluripotent |
| Adult | (tissue or somatic) occur in ‘adult’ tissues such as bone marrow, muscles, brain, used to replace old cells • Multipotent |
| Cord blood | come from umbilical cord blood & placental blood from new born babies - adult somatic • Multipotent |