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Oral Micro
| Question | Answer |
|---|---|
| What are the 5 microorganisms associated with periodontitis? | Porphyromonas gingivalis (P.g) Prevontella intermedia (P.i) Aggregatibacter actinomycetemcomitans (A.a) Tannerella forsynthia (T.f) Treponoma denticola (T.d) |
| What is Dental plaque as a biofilm | cooperating community of microorganisms, arranged in microcolonies, surrounded by protective matrix resistant to antibiotics, anti-microbials, and the host response |
| What is tooth associated subgingival plaque | densely adherent biofilm G+ rods, cocci, filaments facultative aerobes and anaerobes remove by SRP less virulent |
| What is tissue associated subgingival plaque | loosely adherent G- motile anaerobes Spirochetes remove surgically more virulent |
| What is unattached subgingival plaque | free swimming G- motile anaerobes spirochetes remove by flushing more virulent |
| what is gingivitis | reversible G+ cocci and rods G- cocci = # of G+ and G- =% of facultative aerobes and anaerobes |
| What is periodontitis | inflammatory disease of the supporting tissues of the teeth loss of alveolar bone and Periodontal ligament (PDL) |
| What stage is a T cell lesion seen in periodontitis and what is it a clinical sign for | early stage, clinical sign of gingivitis |
| What stage is a B cell lesion seen in periodontitis and what is it | established and advanced stages, chronic gingivitis and periodontitis |
| What are prostaglandins | derived from arachidonic acid by action of cyclooxyrgenase (COX) produce bone resorption their biosynthesis is blocked by NSAIDs can function both in the promotion and resolution of inflammation osteoclastic bone resorption PGE2 |
| What are cytokines | small secreted proteins released by cells and have a specific effect on interactions and communications between cells they are both proinflammatory and anti-inflammatory |
| What is IL-1B? and What is its function? | important cytokine used for bone resorption |
| What is MMP (1&8)? function? | important cytokine used for connective tissue breakdown |
| What is TNFa? Function? | important cytokine used for bone resorption with PGE2 |
| What causes gingivitis? | plaque |
| What forms first in dental plaque | Pellicle |
| What is the plaque matrix composed of | dextrans (glucans) and levans (fructans) |
Created by:
toothfairymeg
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