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Micro final review

micro final review

QuestionAnswer
The 2 domains of life containing prokaryotes Archaea & Bacteria
Microbe with cell wall containing true peptidoglycan Bacteria
DNA to RNA to protein Central dogma in molecular biology
Cells at the base of a biofilm are metabolically inactive giving them this advantage Higher antimicrobial resistance
Type of microbes that are obligate intracellular pathogens Viruses
Comma shaped bacteria Vibrio
Process bacteria undergo when there is insufficient nutrients Sporulation
Condition in which bacteria are actively dividing in the blood Septicemia
Genus of bacteria that will not stain with Gram’s stain as positive or negative Mycobacterium spp
Endotoxin released from Gram-negative bacteria Lipopolysaccharide (LPS)
RNA OR DNA + protein coat Parts of a virus
The presence of this is responsible for tissue tropism Specific receptor site on host cell
Viral form of a retrovirus after it has integrated with host DNA Provirus
Teratogenic virus that pregnant women should guard against Rubella
Reason why viruses are not included in the domains of life They are acellular - not composed of cells
The kind of microbe that causes ringworm A fungus
Cell walls of fungi are made of this Chitin
Causative organism of malaria Plasmodium falciparum
Sequences of eukaryotic genes that code for proteins Exons
Fungal disease that resembles tuberculosis Histoplasmosis
Loss of tertiary structure of protein Denaturation
Terminal electron acceptor in aerobic respiration Oxygen
Purpose of fermentation To regenerate NAD+
What happens if a cell lacks oxygen and appropriate inorganic final electron acceptor It will perform fermentation
What happens when a cell lacks genes to make one or more enzymes in the Krebs cycle It cannot respire aerobically
Transfer of genetic material between two organisms that are not related as parent and offspring Horizontal gene transfer
Uptake of naked DNA from environment Transformation
Change in gene expression without changing base sequence Epigenetic change
In DNA replication, the lagging strand is made from this Okazaki fragments
Process by which mRNA copy is made using DNA as template Transcription
Cells in which telomerase is active Stem cells and germ cells only
Reason why Clostridium tetani grows well in deep tissue It is an obligate anaerobe
Growth phase of bacteria when exponential growth is observed Log phase
Enzyme required for bacteria to grow aerobically Cytochrome oxidase
This is the process by which components of a biofilm determine the density of the population Quorum sensing
Autoimmune skin disease due to excessive epidermal cell turnover Psoriasis
Staining procedure that helps select antibiotic Gram’s stain
Autoclaves are used to kill these things Endospores
Ability of a drug to harm the target microbe without harming the host Selective toxicity
Drug resistance mechanism effective against wide range of antimicrobials Efflux pump
This antibiotic kills bacteria by stopping transpeptidase activity Penicillin
Most common portal of entry of pathogens The respiratory tract
Molecular Koch’s postulates are used to identify this characteristic in pathogens Virulence factor genes
Periods of illness during which a disease can be transmissible All of them
Infected person capable of transmitting disease without showing signs or symptoms Asymptomatic carrier
Secondary infection that can develops when antibiotics kill much of the patient’s normal flora Superinfection
Leukocyte that initiates inflammation Mast cells
Exotoxin that triggers a cytokine storm Superantigen
Cytokine responsible for inflammation Histamine
Process of coating of a pathogen by chemical substance to increase recognition by immune cells Opsonization
Leukocytes that are produced in response to parasites & helminths Eoisinophils
Dendritic cells, macrophages and B cells are all these type of cells Professional antigen presenting cells
Cells that produce and secrete antibodies Plasma cells
This molecule is responsible for activating Helper T cells MHC class II molecule
Situation in which transplanted tissue attacks the host cells Graft vs host disease
The class of antibody that is always produced first in any infection IgM
Rogue form of protein PrP Prion
Type of mutation caused by the deletion of one nucleotide with wide ranging consequences Frameshift mutation
This cell component is found in all types of cells Cell membrane
Genes that will not be found on a plasmid Housekeeping/constitutive genes - required always
Difference between DNA and RNA Nucleotide Uracil (U)
Class of antibody found in secretions IgA
Chickenpox can reemerge as this disease Shingles
Causative organism of neonatal conjunctivitis Neisseria gonorrhoeae
Reason why it is important to vaccinate against Rubella High incidence of congenital infections and birth defects
Causative organism of scalded skin syndrome Staphylococcus spp
Causative agent of the leading cause of preventable blindness (trachoma) Chlamydia trachomatis
Diseases protected by DTap Diphtheria, Whooping cough, & Tetanus
Causative organism of pharyngitis Streptococcus pyogenes
Causative agent of “walking pneumonia” Mycoplasma pneumoniae
The part of the respiratory system where alveolar macrophages defend Lower respiratory tract
Ways by which SARS Cov2 is transmitted Direct contact, droplet, & airborne transmission
Cause of acute glomerulonephritis Sequelae of strep throat
Most common causative organism neonatal meningitis Streptococcus agalactiae
Opportunistic infection in the vaginal tract Candidiasis
Hard painless chancre is a symptom of this STD Stage 1 syphilis
Untreatable STD Genital herpes
Important cariogenic species - causes dental caries Streptococcus mutans
Reason why Helicobacter pylori can survive in the acidity of the stomach Produces the enzyme urease to neutralize acid
Infection characterized by “rice water” stools Cholera
Treatment for most digestive system infections Water, electrolytes, & rest
Bleeding gums is a symptom of this infection Gingivitis
Reservoir of Toxoplasma Cats
Vector of Chagas disease Kissing bug (triatomine bug)
Spirochete that causes Lyme disease Borrelia burgdorferi
Definitive host & intermediate host of malaria Mosquito is definitive, humans are intermediate
Bacteria that uses antigenic variation to avoid immune defenses Borrelia burgdorferi in Lyme disease
Reason why bacterial meningitis and encephalitis are hard to treat Many medicines cannot cross the BBB
Reservoir of Naegleria fowleri Warm freshwater ponds & streams
Autoimmune disease with damage to the myelin sheaths of nerve cells; possible symptoms include muscle weakness, numbness, and problems with memory Multiple sclerosis
Reason for the symptoms of rabies Disruption in neurotransmitter function
Toxin that blocks the release of neurotransmitter GABA that stops muscles from relaxing Tetanus toxin
Only STD caused by a protozoan Trichomoniasis
Created by: Diamond87
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