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Micro final review
micro final review
| Question | Answer |
|---|---|
| The 2 domains of life containing prokaryotes | Archaea & Bacteria |
| Microbe with cell wall containing true peptidoglycan | Bacteria |
| DNA to RNA to protein | Central dogma in molecular biology |
| Cells at the base of a biofilm are metabolically inactive giving them this advantage | Higher antimicrobial resistance |
| Type of microbes that are obligate intracellular pathogens | Viruses |
| Comma shaped bacteria | Vibrio |
| Process bacteria undergo when there is insufficient nutrients | Sporulation |
| Condition in which bacteria are actively dividing in the blood | Septicemia |
| Genus of bacteria that will not stain with Gram’s stain as positive or negative | Mycobacterium spp |
| Endotoxin released from Gram-negative bacteria | Lipopolysaccharide (LPS) |
| RNA OR DNA + protein coat | Parts of a virus |
| The presence of this is responsible for tissue tropism | Specific receptor site on host cell |
| Viral form of a retrovirus after it has integrated with host DNA | Provirus |
| Teratogenic virus that pregnant women should guard against | Rubella |
| Reason why viruses are not included in the domains of life | They are acellular - not composed of cells |
| The kind of microbe that causes ringworm | A fungus |
| Cell walls of fungi are made of this | Chitin |
| Causative organism of malaria | Plasmodium falciparum |
| Sequences of eukaryotic genes that code for proteins | Exons |
| Fungal disease that resembles tuberculosis | Histoplasmosis |
| Loss of tertiary structure of protein | Denaturation |
| Terminal electron acceptor in aerobic respiration | Oxygen |
| Purpose of fermentation | To regenerate NAD+ |
| What happens if a cell lacks oxygen and appropriate inorganic final electron acceptor | It will perform fermentation |
| What happens when a cell lacks genes to make one or more enzymes in the Krebs cycle | It cannot respire aerobically |
| Transfer of genetic material between two organisms that are not related as parent and offspring | Horizontal gene transfer |
| Uptake of naked DNA from environment | Transformation |
| Change in gene expression without changing base sequence | Epigenetic change |
| In DNA replication, the lagging strand is made from this | Okazaki fragments |
| Process by which mRNA copy is made using DNA as template | Transcription |
| Cells in which telomerase is active | Stem cells and germ cells only |
| Reason why Clostridium tetani grows well in deep tissue | It is an obligate anaerobe |
| Growth phase of bacteria when exponential growth is observed | Log phase |
| Enzyme required for bacteria to grow aerobically | Cytochrome oxidase |
| This is the process by which components of a biofilm determine the density of the population | Quorum sensing |
| Autoimmune skin disease due to excessive epidermal cell turnover | Psoriasis |
| Staining procedure that helps select antibiotic | Gram’s stain |
| Autoclaves are used to kill these things | Endospores |
| Ability of a drug to harm the target microbe without harming the host | Selective toxicity |
| Drug resistance mechanism effective against wide range of antimicrobials | Efflux pump |
| This antibiotic kills bacteria by stopping transpeptidase activity | Penicillin |
| Most common portal of entry of pathogens | The respiratory tract |
| Molecular Koch’s postulates are used to identify this characteristic in pathogens | Virulence factor genes |
| Periods of illness during which a disease can be transmissible | All of them |
| Infected person capable of transmitting disease without showing signs or symptoms | Asymptomatic carrier |
| Secondary infection that can develops when antibiotics kill much of the patient’s normal flora | Superinfection |
| Leukocyte that initiates inflammation | Mast cells |
| Exotoxin that triggers a cytokine storm | Superantigen |
| Cytokine responsible for inflammation | Histamine |
| Process of coating of a pathogen by chemical substance to increase recognition by immune cells | Opsonization |
| Leukocytes that are produced in response to parasites & helminths | Eoisinophils |
| Dendritic cells, macrophages and B cells are all these type of cells | Professional antigen presenting cells |
| Cells that produce and secrete antibodies | Plasma cells |
| This molecule is responsible for activating Helper T cells | MHC class II molecule |
| Situation in which transplanted tissue attacks the host cells | Graft vs host disease |
| The class of antibody that is always produced first in any infection | IgM |
| Rogue form of protein PrP | Prion |
| Type of mutation caused by the deletion of one nucleotide with wide ranging consequences | Frameshift mutation |
| This cell component is found in all types of cells | Cell membrane |
| Genes that will not be found on a plasmid | Housekeeping/constitutive genes - required always |
| Difference between DNA and RNA | Nucleotide Uracil (U) |
| Class of antibody found in secretions | IgA |
| Chickenpox can reemerge as this disease | Shingles |
| Causative organism of neonatal conjunctivitis | Neisseria gonorrhoeae |
| Reason why it is important to vaccinate against Rubella | High incidence of congenital infections and birth defects |
| Causative organism of scalded skin syndrome | Staphylococcus spp |
| Causative agent of the leading cause of preventable blindness (trachoma) | Chlamydia trachomatis |
| Diseases protected by DTap | Diphtheria, Whooping cough, & Tetanus |
| Causative organism of pharyngitis | Streptococcus pyogenes |
| Causative agent of “walking pneumonia” | Mycoplasma pneumoniae |
| The part of the respiratory system where alveolar macrophages defend | Lower respiratory tract |
| Ways by which SARS Cov2 is transmitted | Direct contact, droplet, & airborne transmission |
| Cause of acute glomerulonephritis | Sequelae of strep throat |
| Most common causative organism neonatal meningitis | Streptococcus agalactiae |
| Opportunistic infection in the vaginal tract | Candidiasis |
| Hard painless chancre is a symptom of this STD | Stage 1 syphilis |
| Untreatable STD | Genital herpes |
| Important cariogenic species - causes dental caries | Streptococcus mutans |
| Reason why Helicobacter pylori can survive in the acidity of the stomach | Produces the enzyme urease to neutralize acid |
| Infection characterized by “rice water” stools | Cholera |
| Treatment for most digestive system infections | Water, electrolytes, & rest |
| Bleeding gums is a symptom of this infection | Gingivitis |
| Reservoir of Toxoplasma | Cats |
| Vector of Chagas disease | Kissing bug (triatomine bug) |
| Spirochete that causes Lyme disease | Borrelia burgdorferi |
| Definitive host & intermediate host of malaria | Mosquito is definitive, humans are intermediate |
| Bacteria that uses antigenic variation to avoid immune defenses | Borrelia burgdorferi in Lyme disease |
| Reason why bacterial meningitis and encephalitis are hard to treat | Many medicines cannot cross the BBB |
| Reservoir of Naegleria fowleri | Warm freshwater ponds & streams |
| Autoimmune disease with damage to the myelin sheaths of nerve cells; possible symptoms include muscle weakness, numbness, and problems with memory | Multiple sclerosis |
| Reason for the symptoms of rabies | Disruption in neurotransmitter function |
| Toxin that blocks the release of neurotransmitter GABA that stops muscles from relaxing | Tetanus toxin |
| Only STD caused by a protozoan | Trichomoniasis |