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DRUG ICARDS

Methoxyflurane

QuestionAnswer
Mechanism of action Inhaled analgesic Mechanism is unclear
Indications Moderate to severe pain, particularly when there will be a significant delay in an opiate being administered
Contraindication (4) -Known severe allergy -Personal or family history of malignant hyperthermia -Known renal impairment -Methoxyflurane administered within the last week
Cautions (4) -Age greater or equal to 75 years, particularly if frail -Pre-eclampsia, can worsen renal impairment -Administration within a confined space -Acute exacerbation of chronic pain
Pregnancy Can cause temporary drowsiness
Dosage 6 ml for greater or equal to 12 years 3 ml for child less than 12 years
Common adverse effects -sedation -Feeling light headed
Onset duration 1-2 minutes 2-3 minutes
Pharmacokinetics - approximately 20% is exhaled, remainder is metabolised in the liver. -One of the metabolites is fluoride ions, high amounts have been associated with renal impairment and this is the reason for know renal impairment being a contraindication
Created by: nicolaprice01
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