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The Defence System
The immune system, antigens, antibodies, lymphocytes etc
| Question | Answer |
|---|---|
| What is a pathogen? | An organism that causes disease |
| Define immunity | The ability to resist infection |
| What is induced immunity? | the ability to resist disease by producing antibodies caused by antigens |
| What is active immunity? | a person makes their own antibodies |
| What is passive immunity? | foreign antibodies are introduced to the body |
| Name a difference between active and passive immunity | Active- long term immunity Passive- short term immunity |
| Name the two defence systems | the general defence system and the specific defence system |
| What is an antigen? | a foreign molecule that stimulates the production of antibodies |
| What is an antibody? | a protein produced by lymphocytes in response to a specific antigen |
| Name the two types of white blood cell | Monocytes and lymphocytes |
| What do monocytes develop into? | Macrophages |
| What do monocytes do | Destroy pathogens and display antigens on their membranes |
| Where are lymphocytes formed and where are they active? | Formed in the bone marrow and active in the lymphatic tissue |
| Where do T-cells mature? | In the thymus gland |
| Where do B-cells mature? | In the bone marrow |
| What does the general defence system do? | Acts as a barrier against all pathogens entering the body |
| Give examples of the 1st line of defence in the general defence system | skin (physical barrier), blood clotting, respiratory tract (lined with cilia and mucous), HCL in stomach, lysozyme (enzyme in sweat, tears and saliva), nose hairs etc |
| What are defence proteins? | Proteins that destroy viruses and pathogens |
| What do interferons do? | They prevent viral multiplication |
| What in the body attracts white blood cells? | Inflammation, swelling, redness, heat, pain |
| What are big phagocytes called? | Macrophages |
| What is the 2nd line of defence in the general defence system? | Phagocytic white blood cells |
| What do phagocytes do? | They surround and ingest/engulf their prey (pathogens) |
| What are the four types of T-cell? | Helper T-cells, Killer T-cells, Suppressor T-cells and Memory T-cells |
| What is the function of Helper T-cells? | Stimulate B-cells and Killer T-cells |
| What is the function of Killer T-cells? | They cause abnormal cells to burst by producing perforin |
| What is the function of Suppressor T-cells? | They turn off the immune response |
| What is the function of Memory T-cells? | Stimulate B-cells and Killer T-cells |
| What are the two types of B-cells? | Plasma B-cells and Memory B-cells |
| What do Plasma B-cells do? | Multiply to make antibodies |
| What do Memory B-cells do? | Live on after infection to prevent re-infection |
| What does the specific defence system do? | Acts against only specific/particular types of pathogens |
| How does the specific defence system work? | Acts by forming antibodies and by killing infected cells |
| What is another name for the specific defence system? | The immune system |
| Name two ways antibodies are produced in the body in active immunity | Pathogens naturally enter the body and antigens are artificially placed in the body (vaccination) |
| Name two ways antibodies are produced to the body in passive immunity | Baby getting antibodies from placenta or mothers milk and getting an injection of foreign antibodies |