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inflammation
| Question | Answer |
|---|---|
| goals of inflammation | 1. keep the injury contained 2. prevent the spread 3. bring the body's defenses to the region under attack |
| acute inflammation examples | sunburn, basic bug bite, sprained ankle |
| 3 phases of acute inflammation | 1. inc. vascular perm: histamine & bradykinin dilate vessels; wbcs can go to the site on injury 2. cellular chemotoxins: chemical signals attract wbcs +platelets; margination 3. systemic response- how the body responds to the inflammatory mediators. |
| What is margination? | when the wbcs line up along the endothelium and release the inflammatory mediators |
| What is leukocytosis? | elevated number of WBC (>10,000) |
| What is a leukemoid reaction? | severe elevation in number of WBC (>50,000) |
| 5 classic signs of inflammation | 1. Redness (rubor) 2. Swelling (tumor) 3. Heat (calor) 4. Pain (dolor) 5. loss of function |
| what does a shift to the left mean in regard to WBCs? | increased neutrophil production in the bone marrow |
| purulent exudate | pus like |
| transudate exudate | watery fluid (like that causing a pleural effusion) |
| what substance causes fever | pyrogens activate prostaglandins to reset the hypothalamic temperature to a higher temp. |
Created by:
hcollie2
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