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Pharmacology Test #3
Unit 7: Endocrine System Drugs
| Question | Answer |
|---|---|
| What's the term for the release of hormones into the bloodstream? | Endocrine |
| What is the term for releases hormones into ducts i.e. mammary glands, and duodenal loop? | Exocrine |
| Where do "trophic" hormones that cause another gland to release hormones come from? | Anterior pituitary |
| Where do vasopressins, oxytocins, and other direct acting hormones come from? | Posterior pituitary |
| What is caused by surgery, radiation, and drugs that suppress hormone production? | Hyperfunction |
| What is caused by replacing peripheral endocrine hormones with exogenous source hormones? | Hypofunction |
| What is primary endocrine disorders? | Non-functioning |
| What arises from primary or secondary endocrine disorders? | Abnormal tissue |
| What circulates glucose into cells for energy? | Insulin |
| What has the greatest effect on the liver and causes release of stored glucose to bloodstream? | Glucagon |
| What forms when there is too much glucagon? | Fat |
| What disease arises when pancreatic cells do not produce enough insulin? | Type 1 diabetes |
| What disease arises when there is resistance of tissues to insulin that is rare in dogs and happens sometimes in cats? | Type 2 diabetes |
| What is a sign of diabetes when there is frequent urination? | Polyuria |
| What can be placed under the skin (middle third dorsally) of the ear that promotes growth? | Implant of growth-promoting pellet |
| What drug prevents pregnancy after mismating? | Estrogen |
| What drug is injected into mares to induce estrus? It can cause severe anemia and follicular cysts. | Estradiol |
| What is a reproductive hormonal drug that treats urinary incontinence and is available in capsule or tablet form? | Diethystilbestrol |
| What reproductive hormone suppresses estrus and is used to treat false pregnancy and some behavioural disorders in dogs and cats? it mimics progesterone (corpus luteum). | Progestin |
| What is the drug name for the progestin used in mares and gilts Ovaban? | Megestrol acetate |
| What is the drug name for the progestin used in mares and gilts Regumate? | Altrenogest |
| What must be worn when dealing with progestins in order to not effect handlers hormones? | Gloves |
| What reproductive hormone can treat urinary incontinences in males and help produce testosterone for fertility? | Androgens |
| What reproductive hormone is stored in the pituitary gland and used to contract uterine muscles and cause milk let-down? Cannot be used during dystocia. | Oxytocin |
| What reproductive hormone lyses corpus luteum, relaxes cervix, and can sync estrus in cattle? | Prostaglandins |
| What is the drug name for the prostaglandin that you must take precaution when pregnant or have asthma? Common name is Lutalyse. | Dinoprost |
| What is the drug name for the prostaglandin that you must take precaution when pregnant or have asthma? Common name is Esturmate. | Cloprostenal |
| What reproductive hormone drug group mimics GnRH, Luteinizing hormone, and Follicle stimulating hormone? | Gonadotropins |
| What gonadotropin drug treats follicular cysts on the ovaries of cows? | Gonadorelin |
| What is the endocrine drug group that influences the behaviour of other animals? | Pheromones |
| What is a pheromone specifically for cats? It mimics the hormone released by the facial gland to reduce stress. | Feliway |
| What is a pheromone drug specifically for dogs? It mimic the hormone produced by the nursing bitch. | DAP (dog appeasing hormone |
| What endocrine drug acts on the trachea and contains iodine which is absorbed and bound to the amino acid tyrosine? | Thyroid hormone drugs |
| What is the T3 active drug? | Triiodothyronine |
| What is the T4 drug? Converts to T3 after released. | Thyroxine |
| What is the lack of thyroid hormone in dogs that causes goiter gland swelling? | Hypothyroidism |
| What is a drug that is a synthetic version of T4 to all species? | Levothyroxine |
| What is the overproduction of the thyroid hormone in older cats particularly? | Hyperthyroidism |
| What drug treats hyperthyroidism by blocking the thyroid hormone? | Methimazole |
| What is the drug that converts to methimazole after being released? | Carbimazole |
| What treatment is delivered IV to destroy the overproduction of thyroid tissues that is a permanent costly fix? | Radioactive iodine |
| What is the act of removing a thyroid to make hypothyroid and treat with drugs from there? | Thyroidectomy |
| What endocrine drugs produce insulin and glucagon to regulate blood glucose? | Pancreatic hormone drugs |
| Where in the pancreas is insulin and glucagon produced? | Pancreases' islet of Langerhans |
| What is the disease when pancreatic cells can't produce enough insulin or the insulin activity is altered? | Diabetes mellitus |
| What is the short-acting insulin made in London ON? | Regular insulin |
| What is the common name for regular insulin? | Toronto insulin |
| What is the intermediate-acting insulin type used in dogs and cats only? | Caninsulin |
| What is the long-acting insulin that is human label that is used in emergency? | Glargine lantus |
| What is the at home alternative for a pet that has been given insulin without food prior? | Corn syrup |
| What is the less common type of diabetes? | Diabetes inspipidus |
| What is the drug type used to treat diabetes insipidus? | Vasopressin |
| What is vasopressin? | Antidiuretic |
| What endocrine drug is to target the structure cranial to kidneys that produce endogenous corticosteroids? | Adrenal gland hormones |
| What drug treats Addison's disease which is a lack of meneralocorticoid? | Hypoadrenocorticism |
| Name the hypoadrenocorticism drug that starts with F? Common name is Florinef. | Fludrocortisone |
| Name the hypoadrenocorticism drug that starts with D? Common name is Percorten. | Desocycorticoterone |
| What drug treats Cushing's disease, when there are too many corticosteroids from other diseases? The patient may present alopecia and a pendulous abdomen. | Hyperadrenocorticism |
| What is a drug that can manage hyperadrenocorticism and the common name is Lysodren? | Mitotane |
| What is a drug that can manage hyperadrenocorticism and the common name is Vetoryn? | Trilostane |
| What type of endocrine drug is used to control growth, feed efficiency and carcass composition? | Growth-promoting hormones |
| What is the simplest growth-promoting hormone? | Steroids |
| What is a sex steroid that promotes steer growth, anabolic function to stimulate protein synthesis and natural growth? | Estrogen/estradiol |
| What sex steroid is included with estradiol for heifers? | Testosterone |
| What sex steroid slows the release of estradiol? | Progesterone |
| What growth-promoting hormone is synthetic and improves weight and feed efficiency of steers? | Trenbolone |
| What nonsteroidal hormone is synthetic estrogen? | Zeranol |