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Drug of abuse
| Question | Answer |
|---|---|
| 3 drugs metabolise from atypical pseudocholinesteraseerase | Ramifentanyl Succinylcholine Esmolol |
| Treatment of withdrawal syndrome | Clonidine, lufexidine/bzd |
| Prevent withdrawal syndrome | Methadone |
| Prevent relapse | Naltrexone |
| Acute poisoning | Naloxone |
| U receptorfunction | Mnemonics sacrum S sedation A analgesia C constipation R avoid in asthma, COPD U euphoria M meiosis |
| Morphine is avoided in asthma and COPD. Because | Cause severe, respiratory depression |
| Tolerance can occur to all the action of morphine except | 3 c Constipation Construction of pupil Convulsion |
| Absolute contra indication of morphine | Head injury |
| opioid agonist | Stimulate Meow, Ka Baap Delta |
| Opioid, partial agonist | Partial agonist at , mue receptor |
| Opioid agonist antagonist | Agonist on one, kappa, and antagonist on mute |
| Opioid antagonist | Blocks all three receptor |
| Contra indication for infective diarrhoea | Loperamide/Dyphenoxyalate |
| Which drug is given with loperamide to prevent drug abuse | Atropine |
| Which drug stop Spain, bye, meow, Kadapa , Delta but also increase 5HT and NA in spinal cord | Tramadol /tapentadol |
| Which drug causes post-operative muscle rigidity | Fentanyl |
| Which drugs cause post-operative muscle pain? | Succinylcholine |
| Shortest acting opioid | Remi fentanyl |
| Most potent opioid | Sufentanyl |
| Ceiling effect on respiratory depression is by which partial agonist | Buprenorphine |
| What drugs on agonist antagonist? | Mnemonic – PNB Pentazocine Nalbufine Butorphanol |
| Name the opioid antagonist | Naloxone Naltrexone |
| Short, acting, opioid antagonist | Naloxone |
| Long, acting, opioid antagonist | Naltrexone Teri Teri |
| Drug used in alcohol aversion, therapy | Disulphiram |
| Disulphiram like reaction shown by | CG M P Cephalosporins chlorpropamide Griseofulvin Metronidazole Procarbazine |
| Drug of choice for methanol poisoning | Methyl alcohol |
| Drugs, decreasing alcohol craving | Mnemonic none of the above None- naltrexone Of- ondansetron The- topiramate Above- acamprosate |
| Contra indication of disulphiram | In patient with physical dependence |