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Mood disorder
Drugs
| Question | Answer |
|---|---|
| Treatment of acute episode of mania | Secretive(antipsychotic/BZ D) plus lithium |
| Prophylaxis of acute mania | Lithium |
| Actions of lithium | Lithium Action (mnemonic):Leucocyte increase Tremors(most common) Hypothyroidism Increase urine(polyuria) Avoided in Mothers Acne Calcium increase Twave changes Incoordination, ataxia, slurred speech Obesity Nausea, vomiting, diarrhoea Seizure |
| Drugs which increase risk of lithium toxicity | TZD lisinopril Indomethacin |
| Plasma concentration acute mania | 0.8– 1.2 mE per litre. |
| Lithium profile, axis dose | 0.5–0.8 MEQ/L |
| Uses of lithium | Acute mania Bipolar disorder Depression Neutropenia |
| Drug of choice for rapid cyclers in mania | Valproate |
| Typical anti-depressant acts by | Increase 5HT |
| MAO inhibitor | Moclebemide |
| Which Re uptake inhibitor can be used on cardiac patient | Selective reuptake inhibitor |
| Which react take used in severe depression | Nonselective |
| Types of anti-depressant | Typical anti-depressant atypical antidepressant |
| Types of typical anti-depressant | MAO – A Inhibitor Re-uptake inhibitors: NSRI and SSRI |
| Types of atypical anti-depressant | Mitrazapanine (nssa) esKeta mine Brexanolone |
| Drug used in premature ejaculation | Depoxatine |