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Antibiotics
| Question | Answer |
|---|---|
| What are some abx that treat CA-MRSA? | Minocycline, Doxycycline |
| What abx can treat MRSA? | IV Vancomycin, Oral Linezolid. IV Ceftaroline fomasil= 1st cephalosporin to treat MRSA |
| What is Glucocorticoids MOA & therapeutic use? | Prednisone, Prednisolone, Cortisone MOA: lysis of antigen active lymphocytes & suppress proliferation, suppress inflammation & immune response. Use: prevent organ rejection, allergic & autoimmune disorder |
| what are SE & nurse implications of glucorticoids? | increased appetitie, weight gain; monitor daily increase glucose; monitor decreased leukocyte count; what for infection hypertension; monitor TAPER OFF Avoid alcohol & sun |
| What is a immunosuppressant? | Cyclosporine prevents organ rejection in transplants. - AE: Nephrotoxicity, Hepatotoxicity, increased bp, infection |
| what is a cytotoxic drug? MOA? Adverse effects? | Methotrexate -suppresses immune responses by killing B&T lymphocytes that are undergoing proliferation. AE: bone marrow suppression > GI disturbances, neutropenia/thrombocytopenia. |
| What is MOA of Penicillin? | weaken the cell wall, causing bacteria to take up excessive amounts of water & rupture. |
| What are tetracyclines? | Doxycycline Minocycline |
| what are macrolides? | azithromycin erythromycin AE: Steven-Johnson syndrome, ototoxicity, hepatotoxicity, cdiff, hypersensitivity reactions , photosensitivit, N/V/D. |
| Mupirocin | topical abx for impetigo caused by staph aureus: cream applied 3x/day for 10-12 da elimination of nasal colinization by MRSA. |
| What are tetracyclines? | Doxycycline Minocycline |
| what are macrolides? | azithromycin erythromycin AE: Steven-Johnson syndrome, ototoxicity, hepatotoxicity, cdiff, hypersensitivity reactions , photosensitivit, N/V/D. |
| Mupirocin | topical abx for impetigo caused by staph aureus: cream applied 3x/day for 10-12 da elimination of nasal colinization by MRSA. |