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Anatomy 8

integumentary

TermDefinition
integumentary system skin and its accessories: hair, nails, glands, blood vessels, muscles, nerves
dermatology diagnose treatments and disorders in integumentary system
skin cutaneous membrane, covers body and larges organ -2 layers, epidermis and dermis
epidermis outer thin layer of epithelial tissue, keratinized stratified squamous, 4 major cell types
dermis inner thicker layer of connective tissue
subcutaneous or hypodermis beneath dermis, not part of the skin, connective tissue
epidermis cell types keratocytes (keratin), melanocytes (melanin), Langerhans (from bone marrow and immunity), merkel (touch, linked to neuron) cells
keratinocytes 90% of cells in epidermis, produces keratin
melanocytes 8% of epidermis, produces melanin pigment
Langerhans from bone marrow, immunity
merkel deepest layer
stratum basal/germinativum deepest layer, where epidermis is formed (cell division), connected by hemidesmosomes to connective tissue
stratum spinosum 8-10 layers of keratinocytes, desmosomes
stratum granulosum keratinocytes with granules
stratum lucidum represents thick layers of skin (palm of hand, bottom of heels)
stratum corneum composed of flat sublayers, dead keratinocytes that shed
keratinization accumulation of more and more protective keratin, cells move from deep to surface
dandruff
psoriasis 7-10 day skin turn over instead of 4 weeks, flaky skin
dermis contains papillary and reticular region
papillary region top 20% or less, has areolar conn. tissue, all fibers -detects touch and cold, anchors epidermis to dermis
reticular region 80% under papillary, has dense irregular connective tissue with collagen and elastic fibers, detects warm
striae/stretch marks in reticular region, most likely to get stretch marks
dermal papillae finger like projections in papillary region
Meissner corpuscle detects touch, papillary
nociceptor detects pain, everywhere
ruffins corpuscles detects touch, reticular
sebaceous gland attaches to hair follical, marks where the reticular region starts
Pacinian corpuscles
hair root plexus most sensitive receptor, can activate it without even touching the skin
lines of cleavage tension lines of skin, indicate predominant direction of fibers
epidermal ridges reflect contours of underlying dermal papillae to form finger prints
nevus mole, overgrowth of melanocytes
vitiligo loss of melanocytes from patches of skin
carotene yellow-orange pigment
hemoglobin red color
subcutaneous/ hypodermis layer layer of fat
hair/pili protection, reduce loss of head, sensing light touch -dead, made of keratin
hair shaft everything you see
arrector pili smooth muscle in dermis, contracts with cold or fear = goosebumps
function of hair? prevent heat loss, decrease sunburn, sense light touch, protect eyes
blonde or red hair melanin with iron and sulfur
sebaceous (oil) glands has hair, produces sebum (inhibits growth of bacteria)
sudoriferous (sweat) gland c
acne bacterial inflammation of sebaceous glands
eccrine sweat gland (sudoriferous), no hair, found everywhere
apocrine sweat gland (sudoriferous), connected to hair, found in axillary and pubic region
ceruminous (wax) gland makes wax, bug repellant from ear, creates barrier
nails tight keratinized cells, body is pink bc capillaries, lunula is white bc thick root,
cuticle eponychium / stratum cornea
hyponychium secures nail to skin at tip
thin skin covers most of body 4 layers
thick skin covers palms and feet 5 layers
function of skin? reg temp, protection, cutaneous sensation, excretion and absorption
thermoregulation blood/heat sent to surface, leads to sweat to cool down
excretion absorption lose water and salt from skin
transdermal drug administration lets skin absorb drug through patch
basal cell carcinoma rarely metastasizes
squamous cell carcinoma may metastasize
malignant melanomas metastasizes rapidly, most common in young women
Created by: bellai
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