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spiro
Stack #37406
| Question | Answer |
|---|---|
| name the 4 important genera of spirochaetales | treponema, brachyspira, borrelia, leptospira |
| describe the structure of spirochetes | helical, long, slender |
| describe the motility apparatus of spirochetes | protoplasmic cylinder, flagella, sheath |
| what is the primary structure associated with locomotion of spirochetes | sheath not flagella |
| what makes up the outer sheath of the spirochete | peptidoglycan |
| what characteristic is unique to borrelia | requires an insect vector |
| how does leptospira move | rotation around central axis, flexing and translational, undulatory movement |
| describe the movement of brachyspira/treponema | rotation and majestic translational movement and stiff flexion |
| describe the movement of borrelia | frequent reversal of translational movement, cork screw like and lashing |
| order of staining affinity with giemsa stain of spirochetes | borrelia > lbrachyspira/treponema > leptospira |
| all 4 genera of spirochetes have 3 of the same microscopic characteristics, what are they | all are visible by dark field, silver impregnation, and FA technique |
| all but one genera of spirochete reacts with dilute carbol fuchsin (DCF) stain, which one is it | leptospira |
| what characteristic is made visible by use of dark field microscope when dealing with spirochetes | motility |
| what does treponema cause in man | syphillus |
| habitat of treponema/brachyspira | obligate parasites of alimentary and genital tracts |
| cultural characteristics of treponema/brachyspira | anaerobic with CO2, slow growing |
| is it easy or difficult to culture treponema/brachyspira | difficult |
| what does the genera brachyspira cause in pigs | swine dysentery |
| what 3 spp of brachyspira make up the swine dysentery complex | B hyodysenteriae, B pilosicoli, B innocens |
| of the 3 brachyspira spp causing swine dysentery, which is most pathogenic and which is least pathogenic | B hyodysenteriae > B pilosicoli > B innocens |
| where does brachyspira manifest itself in the pig | large intestine |
| describe the dz of swine dysentery | chronic, wt loss |
| what is the case fatality rate of swine dysentery | up to 50% |
| describe the feces of a pig infected with swine dysentery | loose/pasty, gray to black, mucus, blood |
| what is the role of B pilosicoli in swine dysentery | porcine colonic spirochetosis |
| what is porcine colonic spirochetosis | minor version of swine dysentery, renders diarrhea and wasting |
| what kind of dz is swine dysentery | production dz |
| what is the causitive agent of "hairy footwart" | Treponema brennaborense |
| what is another name for "hairy footwart" | bovine PDD, papilomatous digital dermatitis |
| what type of environmental conditions is T brennaborense associated with | wet conditions |
| what does T paraluiscuniculi cause in rabbits | "vent dz" and syphilis |
| what is the causitive agent of vent dz and what spp does it effect | treponema paraluiscuniculi, affects rabbits |
| what are the signs of vent dz and syphilis in rabbits | venereal infection, loss of hair, scabs |
| what are the sources of swine dysentery | PIGS, dogs, mice, guinea pigs, birds |
| which two sources of swine dysentery are most important and why | Pigs (natural host) and Mice (keep it going) |
| how is swine dysentery transmitted | fecal oral |
| how long is swine dysentery shed for | 3m to long term |
| after shedding, can brachyspira spp survive outside the host | yes |
| does brachyspira spread slow or fast within a population | slowly |
| is the spread of brachyspira in populations correlated to its rate of growth in the laboratory | yes, slow spread and slow growth |
| what are the lab diagnostics used on brachyspira | direct microscopy, FAT, histopathology, herd serology, culture |
| what is the best lab diagnostic for brachyspira? worst | FAT is best bc it distiguishes and culture is least bc of its slow growth |
| what is the tx for brachyspira/treponema | organic arsenicals, antibacterials |
| how would you control swine dysentery | minimize fecal contact, strategic drugs, reputable breeders |
| are vaccines available for swine dysentery | no |
| does swine dysentery occur in SPF pigs | ???help |
| how is borrelia transmitted | by blood sucking arthropods |
| what are the 2 phases of borreliosis | blood-borne phase and localization in tissues |
| what does borrelia anserina cause in chickens | avian spirochetosis |
| what ticks transmit avian spirochetosis | Argas spp |
| is avian spirochetosis a dz of young or old | more serious in young |
| signs and symptoms of avian spirochetosis | fever, depression, anorexia, diarrhea |
| what is the case fatality rate of avian spirochetosis | up to 99% |
| causitive agent of lyme disease | borrelia burgdorferi |
| what ticks transmit borrelia burgdorferi | Ixodes spp |
| what is the reservior for borrelia burgdorferi | rodents |
| in what animals does borrelia burgdorferi cause dz | MAN, DOG, cattle, horse |
| what are symptoms of dogs infected with borrelia burgdorferi | fever, leth, arthritis, kidney/heart/CNS dz |
| what is another name for lyme disease in dogs | shifting leg lameness |
| what is the typical skin reaction associated with b burgdorferi in man | bullseye |
| what are the signs of dz in man due to b burgdorferi | stiffness, headache, increased LN, joints, heart, CNS |
| what are the signs and symptoms associated with cattle and horse infected with b burgdorferi | arthritis, uveitis, encephalitis, laminitis |
| what does b theileri cause in bovine | "bovine spirochetosis" |
| what does b coriaceae cause in the bovine | epizootic bovine abortion |
| what tick transmitts b coriaceae | ornithodoros spp |
| what dx techniques are used to dx borrelia | stained smears, wet preps |
| what is the tx for borrelia | antibacterials |
| how is control and prevention of borrelia achieved | tick control and vaccines |
| describe the specific morphology of leptospira spp | hooked at ends, too slender for bright field microscopy |
| where are leptospira most commonly found | urine |
| what 2 things may be added to make leptospira visible | silver impregnate or immunofluoresence |
| what WERE the 2 species of leptospira | L interrogans and L biflexa |
| is L interrogans parasitic or saprophytic | parasitic |
| is L biflexa parasitic or saprophytic | saprophytic |
| what is the common species of leptospira now | L interrogans |
| how many serovars and serogroups are there of parasitic leptospires | 250+ serovars in 23 serogroups |
| what does leptospira and salmonella have in common besides the fact they are cool | both are divided into serogroups |
| in the naming of leptospira spp, what is the species named after | serovar=species name |
| what is the habitat of leptospira...be specific jackass | kidneys of preferred hosts |
| describe the dz severity in incidental vs preffered hosts | more dz in incidental host than in the preffered host |
| what is the atmospheric condition of leptospira | aerobic |
| describe the media requirements of leptospira | fastidious wrt long chain fatty acids |
| what can be said about the antigens of leptospira | complex but important for identification |
| antigens of leptospira are ------ specific | antigens are genus specific |
| how are antigens divided in terms of groupings | serogroups and serovars |
| serogroups are ----- ------ antigens | serogroups are shared major antigens |
| serovars are ------- -------- antigens and give leptospira species their ------ | serovars are different minor antigens and give leptospira its species name |
| describe the host range of leptospiras serovars | serovars have limited host ranges |
| T/F leptospira spp use urease in their pathogenicity | False! No UREASE |
| what serovars of leptospira cause milk drop and abortions in cattle | serovars hardjo and pomona |
| what causes "milk drop" (agalactia) | leptospira serovar hardjo and leptospira serovar pomona |
| what do serovars hardjo and pomona cause in calves | hemoglobinurea and jaundice |
| are sheep commonly infected with leptospira serovars hardjo and pomona | rare |
| describe effects of leptospira serovar pomana in pigs | often inapparent, acute in young, abortions and stillbirths |
| what does leptospira serovars hardjo and pomona cause in the horse | periodic ophthalmia, uncommon |
| which leptospira spp cause acute nephritis in the dog | leptospira serovar icterohaemorrhagiae and leptospira copenhageni |
| what does leptospira canicola cause in the dog | chronic nephritis |
| why does L canicola cause chronic nephritis in teh dog | dog is natural host therefore milder clinical signs and may not even see clinical signs |
| describe leptospirosis in cats | uncommon |
| what does L icterohaemorrhagiae cause in man | Weils disease |
| describe the ID50 of leptospira in maintenance and incidental hosts | maintenance is low and incidental is high |
| describe the LD50 of leptospira in maintenance and incidental host | maintenance is high and incidental is low |
| describe the length of kidney inhabitation of leptospira in maintenance and incidental hosts | maintenance is long term and incidental is short term |
| describe the ease of transmission of leptospira to maintenance and incidental hosts | maintenance is easy and incidental is hard |
| reserviors of leptospira | wild, often rodents |
| describe the survival of leptospira outside of the host | porlonged if protected |
| how is entry to host achieved by indirect contact | mucosae and abraded skin |
| how is entry to host achieved by direct contact | bites, venereal, transplacental, insect vectors |
| describe lab diagnosis of leptospira | darkfield microscopy and fixed preps |
| why do some animals render a false negative test | more chronic = less antibody titer |
| what is the tx for leptospira | steptomycin to stop shedding and long acting tetracyclins |