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Global Health Final

TermDefinition
Malaria Vector-Borne Mosquitos are vector Agent: Parasitic protozoan
HIV Sex/Blood Transmission Male circumcision lowers risk
TB Bacteria: m. tuberculosis Air-Borne (inhalation)
HIV Risk Factors 1. Partner w/high viral load 2. Partner w/ulcerative STIs
TB Treatment Long DOT Expensive
Malaria Symptoms Acute anemia, headache, fever, seizures, coma
Tools to Combat Malaria 1. Drug Therapies 2. Insecticide Spray 3. Insecticide Treated Bed Nets
Neglected Tropical Diseases Impair growth and development and promote poverty Carry social stigma, are deforming/disabling Tend to impact low-income rural areas
HAT Vector-Borne
HAT Vector Tsetse (Biting Fly)
HAT Agent: Trypanosoma (parasitic protozoa)
HAT Treatment Clinic for human infections Monitor patients w/toxic drugs
HAT and LF Population at Risk Sub-Saharan Africa Rural areas of low-income countries Associated with poverty
Lymphatic Filariasis Vector-borne
LF Symptoms Hydrocel Elephantiasis
LF Vector Mosquito
LF Agent Worm
Co-endemic NTDs STHs Schistosomiasis LF Onchocerciasis
Onchocerciasis River Blindness
Onchocerciasis Vector Tiny Black Fly
Schistosomiasis Water-borne Often part of Rapid Impact Package Treated by MDA
STH Food-borne Parasitic Worms
STH Treatment Mass De-Worming
STH Examples Ascariasis Trichuriasis (whipworm) Hookworm
Incidence The number of NEW cases of a particular condition during a time period
Prevalence Current number of people suffering from illness in a given time period
Three Parts of Healthcare System Actors, Resources, and Institutes
Four Elements of Healthcare System Availability, Accessibility, Acceptability, Quality
Goals of Healthcare System Improve population health Respond to expectations Protect against cost
Alma Ata Declaration First attempt to make healthcare a human right Emphasized need to address disparities in healthcare and status between developed and developing
Three Ways Malaria Kills Children 1. Infection in pregnancy 2. Acute Illness 3. Chronic
Infectious Disease Disorders caused by organisms
Onchocerciasis in West Africa Mass De-worming in schools Large success and helped reduce burden of 3 diseases
LF Reduction in China Medicated Salts Lots of people no longer at risk Cheap success
Rapid Impact Package Program providing treatment/prevention of NTDs Contains multiple drugs to simultaneously treat multiple conditions LF, STH, Oncho, Schist, Trachoma
Emerging Infectious Diseases Dengue, West Nile, Zika, E. coli, Flu, SARS, MERS, Covid
Antibody Dependent Enhancement Previous infection = antibodies for one strain More likely to get other strains
Dengue in Asia post WWII Bomb craters, more travel, lack of nutrients and health, and neglected prevention efforts meant increase in prevalence
Asian Tiger and Yellow Fever Mosquitoes Spread Dengue and Zika Got to US in imported cases
E. coli 0157 Virus transferred toxin gene from Shigella (diarrhea causing bacteria) into E. coli Made it harmful to humans
Hemagglutinin and Neuraminidase Proteins on exterior of influenza particles Determines form of disease and thus who can get it Ex H1N1, H5N5
Zika Spread by Asian Tiger and Yellow Fever mosquitos Spread through travel and trade
Factors Influencing Organism Evolution 1. Drug Resistance 2. Genetic Shifts
High Blood Sugar Hyperglycemia Blood sugar is HIGH, insulin is released from BETA CELL, which acts as KEY to let glucose INTO THE CELL, which LOWERS amount of sugar in the blood
Low Blood Sugar Hypoglycemia When blood sugar is LOW, GLUCAGON is released from ALPHA CELL, which then signals cells to let glucose OUT of the cell and into the BLOOD
Diabetes Epidemic Increased survival rate, aging population, population growth, diet/cultural changes
Type 2 Diabetes Chronically high glucose Can make cells insulin intolerant (cells stop listening to insulin signals)
Type 2 Consequences Econ burden on families and society Long term failure of various organs (kidneys, eyes, limbs) Can lead to amputation Societal Burden: loss of labor, premature death
Type 2 Diabetes Treatment Stop/change bad habits, change lifestyle, add exercise
Type 1 Diabetes Treatment Synthetic insulin
Nutrition in Type 2 Prevention Focus on diet, monitor diet and count carbs Reduce processed foods and added sugar Increase whole grains/fiber/fruits and veggies
Bioactive Phytonutrients Nutrient/chemical from plants that initiates bio reactions in humans when consumed
Bioactive Phytonutrient Examples Carotenoids, Anthocyanins, caffeine, nicotine, morphine, etc.
Bioactive Phytonutrients: Misleading Benefits There are many places these COULD BE in metabolism, so no one really knows if they will help
Dietary Supplements Intended to supplement diet NOT treat, prevent, or cure disease
Dietary Supplements Consumer Belief Belief in healing effects, but there is no evidence/oversight/testing on most supplements on the market
Main Point of Food/Plant Supplements Supplements do not equal food
Morbidity Suffering from a disease
CVD Number one killer of adults everywhere except Africa
CVD Deaths 30% of deaths globally
Poland Case Study Men dying early due to intense smoking Passed legislation, added taxes, started warning labels, smoke-outs, etc. Successfully changed outcome
Tipping Point Point of no return for environmental changes and ecosystem services
Ecosystem Services Benefits people obtain from natural environment and functioning ecosystems
Sahel Tipping Point Overgrazing and dryland agriculture combined w/replacing shrubs w/farmland Large amounts of topsoil lost and lost ability to support human communities
Himalayan Glaciers Melting harms major rivers in S. Asia, as most of them get their water from seasonal meltings As they melt, too much water, once its gone, not enough
Mountain Pine Beetle Epidemic Drought/warm weather/fires/dying pines can't protect from thriving beetles
Sea Surface Temp/Sea Level Rising Temps rising = impact on marine life
Great Barrier Reef Warmth = bleaching/acidification Home to biodiversity
Climate Change and Midwest Species N-S Temp Gradient W-E Moisture Gradient Hares, birds, and plants all experienced changes
SDG 14- Life Below Water Huge source of food and labor for humans
5 Major Threats to Human Health 1. Climate Change 2. Stratospheric Ozone Depletion 3. Biodiversity Loss and Ecosystem Function 4. Freshwater Decline 5. Desertification and Land Degradation
Created by: Eliana.s
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